The pleuropulmonary solitary fibrous tumour (SFT) is a rare type of tumour. This paper outlined a 63-year-old female who came to the hospital with two weeks history of chronic cough, shortness of breath, and hypoglycemia. Contrast-Enhanced CT Thorax showed a huge heterogeneously-enhancing mass occupying the right hemithorax. US-guided biopsy followed by histological examination showed the features of an SFT. In view of the association between pleuropulmonary SFT and hypoglycaemia, the patient was highly likely to be suffering from a paraneoplastic syndrome known as Doege-Potter Syndrome.International Journal of Human and Health Sciences Vol. 05 No. 02 April’21 Page: 251-253

Abstract:Schwannomas are benign tumors arising from Schwann cells of the sheaths of peripheral nerves. Although vagus nerve and sympathetic chain composed of sympathetic fibers is one of the most common sites of schwannomas in extracranial head and neck region, many cases of origin unknown schwannomas were reported. We report an unusual rare case of a submandibular gland schwannoma in a 67-year-old lady, who was successfully treated by surgical excision with no cranial nerve deficits and complete resolution of the symptoms postoperatively. In this report, we establish a rare findings of schwannoma of the submandibular gland and to the best of our knowledge, this is the first case-report of schwannoma of submandibular gland reported from a tertiary hospital in the east coast of Malaysia.

Thiopurine exposure from inflammatory bowel disease (IBD) treatment had been associated with a higher risk of lymphoproliferative disorders namely peripheral T-cell lymphoma, as early as 2 years after its initiation. We report a rare case of classical or type 1 enteropathy-associated T-cell lymphoma (EATL) with liver metastasis in a long-standing Crohn’s disease 61-year-old patient treated with azathioprine monotherapy. He presented with acute, severe abdominal pain with cholestatic jaundice and pancytopenia. Colonoscopy showed multiple small, superficial ulcers at the terminal ileum and the biopsy taken was reported as classical EATL, an uncommon gastrointestinal non-Hodgkin’s lymphoma with CD2, CD 3, CD 30, and CD 56 positivity and more than 90% Ki67 proliferative index. Computed tomography (CT) 3-phase liver scan suggested liver metastasis. This case highlights the unusual presentation of classical EATL in non-celiac disease patients and its risk association with thiopurine therapy in IBD.