La barchata (Ziziphus obtusifolia [Hook. ex Torr. & A. Gray]) es un arbusto común en el noroeste de México. Esta planta se utiliza tradicionalmente para combatir padecimientos gastrointestinales y degenerativos. En el presente trabajo se evaluó la capacidad antioxidante y antimicrobiana de extractos obtenidos de ramas de barchata. Se obtuvieron extractos con diferentes solventes: etanol acidificado (EtOH-ac) y agua (Ac). A cada uno se le evaluó su capacidad antioxidante medida por la inhibición del radical ABTS, DPPH, y la prueba de hemólisis. La actividad antimicrobiana se realizó en Escherichia coli y Staphylococcus aureus y en paralelo se evaluó el efecto antiviral, utilizando al bacteriófago Av08 como modelo enteroviral. Los extractos Ac y EtOH-ac, inhibieron los radicales ABTS y DPPH mostrando valores desde 17.41 ± 0.02 a 25.03 ± 3.73 mmol/ETge, respectivamente. En la prueba de hemólisis se encontraron porcentajes de inhibición más elevados en el extracto Ac con 46.3 %, mientras que en el etanólico fue de 36.8 %. En la The barchata (Ziziphus obtusifolia [Hook, ex Torr. & A. Gray]) is a common shrub in northwestern Mexico. This plant is traditionally used to combat gastrointestinal and degenerative diseases. In the present work the antioxidant and antimicrobial capacity of extracts obtained from barchata branches was evaluated. Extracts were obtained with different solvents: acidified ethanol (EtOH-ac) and water (Ac). Each one was evaluated for its antioxidant capacity measured by the inhibition of the ABTS radical, DPPH, and the hemolysis test. The antimicrobial activity was carried out in Escherichia coli and Staphylococcus aureus and in parallel the antiviral effect was evaluated, using the Av08 bacteriophage as an enteroviral model. Ac and EtOH-ac extracts inhibited ABTS and DPPH radicals, showing values from 17.41 ± 0.02 to 25.03 ± 3.73 mmol/ETge, respectively. In the hemolysis test, higher
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