D 24 31 108 43'* Survey Number (see footnote8); the five-digit numbers are DR = drug repository, National Institutes of Health.6 For quinine equivalents see (3). °Refers to analyses listed in Table IV. d Melts with decomposition. * These yields refer to highly purified material. / See experimental section. g Absolute ethanol was used as the reaction solvent. h For the data on the other product isolated from this reaction, see D. *' Yield after one recrystallization. > Yield after several washings with ethanol. * For the data on the other product isolated from this reaction, see C.1 Originally prepared (4c) by heating dibenzoylmethane with excess morpholine; m.p. 96-97°. A mixture melting point of samples prepared in the two ways showed no depression. Acid hydrolysis gave dibenzoylmethane. m Distilled ßmethoxybenzalacetophenone was used as starting material. " Allowed to stand overnight in the refrigerator. p Solubility: in water at 25°, 0.05 g. per 100 ml.; at 90°, 0.1 g. per 100 ml.; in 3 N HC1 at 25°, 1.0 g. per 100 ml.the high antibacterial activity of benzalacetophenone and dibenzoylethylene in mind [cf. (8)].9Absorption spectra of six of these compounds10 over the wavelength range 8 The following tests on substituted chalcones were carried out at the Lilly Research

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