This study reports on some of the employment trends and skill requirements in the information systems area as seen by the information systems managers of 32 of the nation's largest organizations. The data was gathered via persona/interviews and questionnaires. We believe the results to be quite interesting in terms of both work force projections and the perceived job skills that are required for programmers, systems analysts, and data processing managers.

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A method is described for the determination of GFR and ERPF using a combined injection of 51Cr-EDTA and 125I-iodohippurate. Plasma samples obtained at 60 min and 150 min after administration were used to determine a flow rate F assuming a monoexponential clearance of the tracers. Empirical relationships were found between F and the true GFR and ERPF determined from multiple sampling and multi-exponential analysis of the clearance curves. The method was shown to be superior to previously published methods involving one or two samples. GFR was calculated with a standard deviation (SD) of only 3.3 ml/min when compared to the multiple sample technique (the reference method), whereas the best estimate from a single sample had a SD of 6.3 ml/min. An improvement in accuracy of ERPF estimation was achieved for values of flow of less than 200 ml/min when the SD was only 9.3 ml/min.

It would seem in this age where much is heard of the "information explosion," the last thing the world needs is an automatic system for the generation of data. And yet, there are many instances in management systems design where such a system is very useful.

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