Background and Objective: Schistosomiasis, the worldʼs second-largest parasitic endemic, is a disease caused by worms of the genus Schistosoma. This study aimed to determine the prevalence and risk factors associated with schistosomiasis in the city of Galim. Materials and Methods:A cross-sectional study was conducted in the city of Galim from March to June, 2020. Urine and stool samples from 320 participants aged 5 to 75 years, from five, randomly selected neighborhoods (Menazoh, Tatah, Mifi, Urban Centre and Haoussa) were examined using the Kato-Katz qualitative and semi-quantitative method and the centrifugal technique respectively to identify and count Schistosoma mansoni and Schistosoma haematobium eggs. A semi-structured questionnaire was administered to participants to obtain socio-demographic data and risk factors. Results: The overall prevalence of schistosomiasis was 1.88%, with 1.25% for Schistosoma haematobium and 0.63% for Schistosoma mansoni. Infections concerning age, sex, neighborhood and occupation showed no significant difference. However, there was a significant difference between schistosoma infection with respect to the level of education (X 2 = 8.22, ddl = 3, P = 0.04). The overall parasite load was 9 eggs/10 mL of urine and 168 eggs per gram (Epg) of stools with an average of 2.25 eggs/10 mL of urine in females and 84 Epg of stools in males. Participants aged 10 to 20 and 20 to 35 years had high parasite loads of 3 eggs/10 mL of urine, respectively. Also, people who visited the Mévobo River (OR =2.22) and contaminated water (OR = 67.78) to wash and/or bath had a high risk of contracting this disease. Conclusion: The overall prevalence of schistosomiasis observed in this region shows that the region is a low-risk area. This region requiring mass care and increased awareness campaigns to completely eradicate the disease.