Covid-19 is usually severe and represents a poor outcome, particularly in patients who have underlying co-morbidities. Among end-stage renal disease patients dependent on dialysis, covid-19 was related to increased morbidity and mortality. There is no causative therapy currently for covid-19. Thus prevention is mainly the best attempt to limit the burden of the disease. The preventive measure may depend on vaccination and public behavior in controlling the spread of the SARS-CoV-2. In the setting of the dialysis center, the patients' and caregivers' compliance with preventive measures is critical in preventing the spreading of Covid-19. The individual's knowledge and attitudes of COVID-19 are likely to influence individual adherence. Evidence suggests that an individual’s knowledge is critical in combating pandemics. Current community service was aimed to increase family caregivers of dialysis patients’ knowledge on covid-19 prevention.

Chronic kidney disease (CKD) patients undergoing hemodialysis have an increase in proinflammatory cytokines. The quality of life of chronic kidney disease patients undergoing hemodialysis is affected by inflammation. Assessment of quality of life in CKD is done using the Kidney Disease Quality of Life Short Form Survey 36 questionnaire (KDQOL SF-36). Garlic (Allium sativum) has anti-inflammatory components. This study was conducted to determine the effect of giving garlic extract on the KDQOL score of the physical and mental health subscale at Mohammad Hoesin General Hospital, Palembang. The study was conducted in the Hemodialysis Room of Moh Hoesin General Hospital, Palembang. Department of Internal Medicine, RSUP Dr.. Moh Hoesin Palembang met the inclusion criteria consecutively in January 2022. Statistical analysis was carried out using the SPSS version 25.0 program. A total of 40 subjects participated in the study, 60% of whom were male. The mean age in the garlic extract group was 45.5 (28-58), and in the placebo group, 55 (26-59). Characteristics of the KDQOL value of the SF-36 physical health subscale with a value of 45.75 ± 22.08 in the garlic group with a significant increase (p = 0.041), the KDQOL value of the SF-36 mental health subscale with a value of 63.26 ± 20.56 in the group garlic with a significant increase (p=0.001). Garlic extract was shown to reduce the inflammatory process, followed by an increase in the KDQOL SF-36 score on the physical and mental health subscale.