Background Wire localization is historically the most common method for guiding excision of non-palpable breast lesions, but there are limitations to the technique. Newer technologies such as magnetic seeds may allow some of these challenges to be overcome. The aim was to compare safety and effectiveness of wire and magnetic seed localization techniques. Methods Women undergoing standard wire or magnetic seed localization for non-palpable lesions between August 2018 and August 2020 were recruited prospectively to this IDEAL stage 2a/2b platform cohort study. The primary outcome was effectiveness defined as accurate localization and removal of the index lesion. Secondary endpoints included safety, specimen weight and reoperation rate for positive margins. Results Data were accrued from 2300 patients in 35 units; 2116 having unifocal, unilateral breast lesion localization. Identification of the index lesion in magnetic-seed-guided (946 patients) and wire-guided excisions (1170 patients) was 99.8 versus 99.1 per cent (P = 0.048). There was no difference in overall complication rate. For a subset of patients having a single lumpectomy only for lesions less than 50 mm (1746 patients), there was no difference in median closest margin (2 mm versus 2 mm, P = 0.342), re-excision rate (12 versus 13 per cent, P = 0.574) and specimen weight in relation to lesion size (0.15 g/mm2  versus 0.138 g/mm2, P = 0.453). Conclusion Magnetic seed localization demonstrated similar safety and effectiveness to those of wire localization. This study has established a robust platform for the comparative evaluation of new localization devices.

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Introduction: Tranquility therapies have recently been more popular as a means of reducing anxiety amongst children in the course of painful diagnostic and therapeutic procedures. As a result, a variety of techniques (oral tranquility, intravenous (IV) tranquility) have been developed to assist practitioners in order to deal with such instances. The goal of this trial was to see how effective propofol could be in calming anxious youngsters during the course of dental therapy. The interventional investigation was undertaken at the Hazaribag College of Dental Sciences and Hospital in Jharkhand. Materials and Methods: To assess the outcomes of intravenous propofol on their performance in the course of therapy, 40 children within the age group of 3–6 years pursuing good physical health but uncooperative in nature (negative or definitely negative, bestowing to Frankel's performance scale) were comprised in the study. The performance rating scale was utilized to assess their performance throughout the therapy (BRS). In addition, the point of tranquility was assessed beforehand. Mann–Whitney U test was utilized to equate male and female points of performance along with gradations of drowsiness. The P value for significance was fixed at 0.05. Results: All participants' performance and point of tranquility in the course of therapy were promising, and therapy was accomplished for everyone. Mann–Whitney U test revealed no statistically significant differences in point of performance, or gradation of drowsiness amid males and females. Pearson's correlation coefficient revealed a strong positive association of therapy time with awakening time. Conclusion: Intravenous propofol deep tranquility in the presence of an anesthesiologist was found to be beneficial in restraining nervous and recalcitrant youngsters in the course of dental therapy.

Background: A child's oral health is critical to his or her general health as well as well-being, and it is one of the foundations for a disease-free life. Because a parent or caregiver plays such a significant part in a child's life, their understanding together with attitude toward oral health will have a significant influence on the child's oral healthiness. Aim: The goal of this research is to assess oral health expertise among parents of children within the age group of 6–12 years in Hazaribag and its link to their children's dental health. Materials and procedures: The research comprised 200 parents of children aged 6–12 years old who had no systemic illness or pathology. The parents were given a detailed questionnaire with apparent validity that included questions on their perspectives about their children's dental health awareness, caries avertion, and the significance of food. SPSS 23 was used to do statistical analysis on the data. Results: The findings indicated that children of parents with a poor understanding of oral health had higher decaying, missing, as well as filled teeth (DMFT/dmft) scores than children of parents with a good understanding of oral health. Conclusion: It is critical for parents to be educated about oral health in order to maintain their children's oral health.