Abstrak Kejadian preeklampsia di Kabupaten Brebes meningkat dari tahun ke tahun. Pada tahun 2011 sebanyak 215 kasus (1.547 persalinan), tahun 2012 sebanyak 170 kasus (1.957 persalinan), tahun 2013 sebanyak 225 kasus (1.811 persalinan) dan tahun 2014 sampai dengan bulan September sebanyak 180 kasus (1.316 persalinan). Tujuan penelitian ini adalah mengetahui faktor risiko yang berhubungan dengan kejadian preeklampsia pada ibu hamil di RSUD Kabupaten Brebes tahun 2014. Jenis penelitian ini adalah survey analitik dengan pendekatan case control . Sampel sejumlah 145 orang untuk masing-masing kelompok kasus dan kontrol yang diambil dengan teknik simple random sampling. Analisis data menggunakan uji chi square dengan derajat kemaknaan (α) = 0,05. Hasil penelitian menunujukan bahwa faktor risiko yang berhubungan dengan kejadian preeklampsia adalah umur (p value = 0,0001; OR = 15,731), status gravida (p value = 0,009; OR = 2,173), riwayat keturunan ( p value = 0,033; OR = 2,618), pemeriksaan antenatal ( p value = 0,0001; OR = 17,111), riwayat preeklampsia (p value = 0,0001; OR = 20,529), riwayat hipertensi ( p value = 0,0001; OR = 6,026). Variabel yang tidak berhubungan adalah jenis pekerjaan, tingkat pendidikan, riwayat diabetes mellitus, dan riwayat kehamilan ganda. Abstract The incidence of preeclampsia in Brebes District was increasing from year to year. In 2011 there were 215 cases (1,547 births), in 2012 there were 170 cases (1,957 births), in 2013 there were 225 cases (1,811 births) and until September 2014 there were 180 cases (2,316 births). The purpose of this research was to determine the risk factors associated with the incidence of preeclampsia in pregnant women from Brebes district hospital in 2014. This research was an analytical survey with case control approach. The total sample was 145 people for each case and control group which was taken with simple random sampling technique. The data was analyzed using chi-square test with α = 0,05. The results of this research showed that the risk factors associated with the incidence of preeclampsia was age (p value = 0,0001; OR = 15,731), gravida status (p value = 0,009; OR = 2,173), heredity profile (p value = 0,033; OR = 2,618), antenatal examination (p value = 0,0001; OR = 17,111), history of preeclampsia (p value = 0,0001; OR = 20,529), history of hypertension (p value = 0,0001; OR = 6,026). The variables that were not related was the type of work, level of education, history of diabetes mellitus, and history of multiple pregnancy.
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