Introduction: Osteoarthritis (OA) is estimated to be the eleventh leading cause of disability worldwide. In Asian countries, OA is much less well-known than in the caucasian population and strongly associated with aging. Therefore, this article focuses comprehensively on the prevalence, risk factors and primary prevention for OA identified in Asian countries.   Methods: This scoping review used the methodological framework by Arksey and O'Malley (2005). Pertaining to this topic, a comprehensive search on academic journals published from 2008 to 2018 (English) was conducted.   Results: A total of 30 studies were selected in this review from 221,510 studies screened from electronic databases. The overall prevalence of OA is in a range of 20.5% to 68.0%. Most of the Asian populations reported to have knee OA in a range of 13.1% to 71.1% in various Asian countries. Risk factors that have been associated with OA are advanced age, being the female and obesity. Osteoporosis, higher body mass density, low level of education, family history of OA, smoking and environmental factors appeared as significant risk factors for OA. A strategic method of primary prevention for OA through lifestyle modification is reducing obesity and treating concomitant cardiovascular disease. Conclusion: Determining OA prevalence and risk factors will provide important information for planning future cost-effective preventive strategies.

The World Health Organization estimated Osteo-Arthritis (OA) to cause 80% sufferers to have movement limitation and 25% unable to perform major daily activities, which result in quality of life deterioration. This study aims to determine the factors associated with Health-Related Quality Of Life (HRQOL). A total of 131 OA patients were involved in a crosssectional study which were recruited from the Rehabilitation Health Organization, Terengganu. Socio-demographic, clinical and lifestyle histories, and 24-hour dietary intake were assessed by using structured questionnaire while HRQOL was measured by using the Malay version of the Osteo-Arthritis Knee and Hip Quality Of Life (OAKHQOL) questionnaire. OAKHQOL questionnaire was evaluated via Likert scales in the items range from 0 (best) to 10 (worst). In each domain, the mean score of the items was calculated, yielding a score for each domain. The score is the standardized on a scale from 0 (best possible QOL) to 100 (worst possible QOL) scale. Anthropometric measurement was measured by using Tanita Body Fat Monitor and Seca height scale and Body Mass Index (BMI) was calculated. Multiple linear regression was performed. Age was positively associated with social functioning (p=0.005). Meanwhile, disease duration was positively associated with physical domain (p=0.043). Among the anthropometric measurement, only BMI was positively associated with physical domain (p=0.040). Higher vitamins C and D intake was associated with lower mental health. Next, better social functioning was observed in low vitamin K consumption. Patients who exercise were associated with better physical and mental health, lower pain, and greater social support. Monthly income, body mass index, waist circumference, and other nutrients intake were not associated with HRQOL. In summary, exercise was the best predictor for better HRQOL.