This research aimed to assess the knowledge and awareness of healthcare providers about perinatal depression and the factors associated with it. Methodology: A quantitative cross-sectional study was conducted on Maternal and Child Health (MCH) clinics in Kuantan, Pahang.healthcare practitioners (HCPs) completed the survey, which consisted of items and items for knowledge and awareness, respectively. Results: The participants' mean knowledge and awareness scores were . and . , respectively. The results showed low level of knowledge and moderate awareness on perinatal depression (PND) among the HCPs. Medical doctors and single-respondents had a higher mean knowledge score on PND (P< . ). Most HCPs scored above % on symptom-related questions and postpartum depression management.Only . % and . % of them scored the questions related to risk factors and treatment for antenatal depression. Recommendation: Continuing professional education is necessary in order to improve the levels of comprehension of PND among HCPs in the Kuantan.