Aim
Servo‐controlled therapeutic hypothermia is a routine therapy for babies with hypoxic‐ischaemic encephalopathy in the neonatal unit and is delivered in designated cooling centres. It is increasingly being used during neonatal transport in the UK to deliver this therapy in a timelier manner for babies not born in a cooling centre. Prior to the implementation of this treatment, passive cooling alone was used in transport. Comparison of passive and servo‐controlled cooling during neonatal transfers with reference to: (i) the proportion of babies in the therapeutic range (33–34°C) at three time points during the transport mission (arrival of the team at the referring unit, departure of the team from the referring unit and at the completion of transport); (ii) the proportion of babies overcooled at any point once the transport team was present (<33°C); and (iii) duration of phases of the transfer to evaluate the impact of active cooling on how long it takes to undertake transfer.
Methods
This was a retrospective observational study comparing babies with passive and servo‐controlled hypothermia (January 2015 to May 2016) following introduction of the servo‐controlled cooling mattress.
Results
A total of 48 patients were treated with hypothermia in transit (29 passive, 19 servo‐controlled). The median gestational age (GA) was 40 weeks (interquartile range: 39–41) and mean birthweight (BW) 3420 g (standard deviation 600 g); there was no differences in GA, BW and clinical characteristics between the groups. There was a statistically significant difference in the temperature at the end of the transport, where 94% (n = 18) of babies who received servo‐controlled cooling were in the target temperature in comparison with only 65% (n = 19) of the passive cooling group babies (P = 0.045). In addition, none of the babies in the servo‐controlled group were warm (>34°C) at the end of the transfer. Babies who underwent servo‐controlled cooling are more likely to maintain a target temperature (33–34°C) (17 (89%) vs. 17 (58%), P = 0.021); in particular, there is less overcooling (<33°C) in this group (2 (10%) vs. 15 (51%), P = 0.004). Total mission time was not significantly different.
Conclusion
The use of servo‐controlled cooling devices during neonatal transport improves the ability to maintain the baby's temperature within the target range (33–34°C) with less overcooling.
Objective The aim of the study is to describe the status of perinatal mortality (PM) in an Indian rural hospital.
Study Design Retrospective analysis of data was compiled from PM meetings (April 2017 to December 2018) following “Making Every Baby Count: audit and review of stillbirths and neonatal deaths (ENAP or Every Newborn Action Plan).”
Results The study includes 8,801 livebirths, 105 stillbirths (SBs); 74 antepartum stillbirths [ASBs], 22 intrapartum stillbirths [ISBs], and nine unknown timing stillbirths [USBs]), 39 neonatal deaths or NDs (perinatal death or PDs 144). The higher risks for ASBs were maternal age >34 years, previous history of death, and/or SBs. Almost half of the PDs could be related with antepartum complications. More than half of the ASB were related with preeclampsia/eclampsia and abruptio placentae; one-third of the ISB were related with preeclampsia/eclampsia and gestational hypertension, fetal growth restriction, and placental dysfunction. The main maternal conditions differed between PDs (p = 0.005). The main causes of the ND were infections, congenital malformations, complications of prematurity, intrapartum complications, and unknown. The stillbirth rate was 11.8/1,000 births, neonatal mortality rate 4.4/1,000 livebirths, and perinatal mortality rate 15.8/1,000 births.
Conclusion This is the first study of its kind in Andhra Pradesh being the first step for the analysis and prevention of PM.
Key Points
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