for treatment of symptomatic uterine leiomyomas. Additionally, objective post-operative outcomes such as post-operative pain, hospitalization length, time until return to work will be compared between the two groups.DESIGN: Prospective, non-randomized cohort study in a community teaching hospital. MATERIALS AND METHODS: All patients undergoing either laparoscopic or abdominal myomectomy who meet study criteria were invited to complete surveys to evaluate the post-operative experience and satisfaction at 3 months, and at 6 months after the surgery. The type of surgery (abdominal or laparoscopic myomectomy) was determined by the attending physician.RESULTS: Patient satisfaction was high in both groups. As expected, blood loss and length of stay was significantly lower in the laparoscopic group. The abdominal myomectomy patients had significantly more fibroids and a higher BMI, but the total hospital charges were lower in this group. There was a trend to earlier ''full recovery'' for laparoscopy patients. The BMI, number of fibroids, and percentage having abdominal myomectomies were higher in African-American women. The uterine fibroid symptom and quality of life scores at baseline and 6 months were not different between the groups. SEXUALITY P-196 GYNECOLOGICAL SURGERY AND SEXUAL FUNCTION.
The energy demand during physical exercise causes an increased oxygen uptake and supply to active tissues, which may increase the rate of free oxygen radical production and thereby affect the capacity of endogenous cellular defense systems. This could result in DNA base modifications, among which 8-hydroxydeoxyguanosine (8OHdG) is one of the most important and has widely been used as a biomarker of in vivo oxidative lesions. Therefore, we examined the effect of regular running exercise on the urinary levels of 8OHdG in 32 long-distance runners and in a group of untrained healthy subjects. The range of 8OHdG in urine was 0.12-6.45 mumol/mol creatinine in both groups, and no significant difference in the mean excretion levels between runners and control probands was observed. This gives no reason to believe that physical exercise in trained individuals may induce a disturbance of the oxidant-to-antioxidant balance.
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