Microorganisms adhere themselves with different surfaces like indwelling medical devices, equipment's of different industries like water, food and dairy products etc. Microorganisms after attachment produce EPS, which help them in the development of biofilms. Commonly known pathogens including, bacteria, fungi, viruses, protozoa and pathogenic cyanobacteria, are involved in biofilm formation. Biofilms are involved in many persistent and chronic infections in human and animals, increase resistance to antimicrobials, biofouling of water and spoilage or contamination of food and dairy products etc. Biofilms producing bacteria is a serious threat for public health globally but due to poor sanitary conditions and low economic resources chances of infections is high in developing countries. Effective control measures should be developed for the treatment and prevention of biofilm to get rid of serious problems.
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