Many researchers used gauge data from weather stations for rainfall estimate across Africa. Since Africa lies within the tropics, there is possibility for variations in rain received from place to place. Therefore, there is need for excessive density of the gauges for accurate estimate of Africa’s rainfall. Due to numerous challenges, these cannot be achieved. This necessitates the application of remote sensing and GIS to detect changes in rainfall amount in Africa between 1999 and 2018. The data used was obtained from remote sensing satellite (TRMM) and analyzed using GIS application (IDRISI Taiga). The Simple Image Differencing was performed on the two annual mean images covering January to December, 1999 and January to December, 2018. This provides reliable information on rainfall estimate that can complement sparsely and unevenly distributed rain gauge network in Africa. The analysis shows that latitudinal locations, to some extent, determine spatial distribution of rainfall in Africa. It is also observed that significant changes in rainfall rate are mainly found around coastal regions. It was recommended that adequate ground data it needed to confirm these findings. African countries should provide adequate and justly distributed weather stations with on-net database for easy access to the data.