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Abstract. The dependences of the point defect concentration (interstitial atoms and vacancies) on the deformation degree were calculated for the L1 2 alloys with the high and low antiphase boundaries (APB) energy in terms of the mathematical model of the work and thermal strengthening of the alloys with the L1 2 structure; the concentration of the point defects generated and annihilated in the process of deformation was estimated. It was found that the main part of the point defects generating during plastic deformation annihilates, the residual density of the deformation point defects does not exceed 10 -5 .