Objectives:Experimentally evaluate the effect of hypovolemia in acute traumatic spinal cord injury.Methods:Twenty adult male Wistar rats were submitted to traumatic spinal cord injury through spinal cord contusion by direct impact. Ten animals were subjected to bleeding of 20% of their estimated blood to simulate a hypovolemic condition after spinal cord contusion and 10 animals were used as control. The animals were evaluated before, 1, 3, 7 and 14 days after the production of the spinal cord injury through behavioral tests (inclined plane test and motor assessment).Results:The spinal cord contusion associated with hypovolemia had a negative influence on functional outcomes of the spinal cord injury. The animals submitted to hypovolemia after spinal cord contusion had lower scores in behavioral tests (inclined plane test and motor assessment), presenting a slower recovery of the motor function.Conclusion:In the experimental model used, the group of animals with hypovolemia after traumatic spinal cord injury had slower recovery and lower intensity in behavioral tests.
ed with development of ADHD in later childhood. Significant relationships were found between sleep disord e r s and pharmacotherapy (p<0.01); comorbidity (p<0.01); and greater adherence to treatment prescribed for symptoms of ADHD (p<0.05).Conclusion: Sleep disorders evaluation should be c o n s i d e red before starting drug treatment for ADHD because diagnostic criteria for ADHD based on DSM-IV or ICD-10 do not differentiate between children with and without sleep disorders. Assessment for sleep disorders may provide a new treatment opportunity for some ADHD children. Future research is needed to clarify the relationship between sleep disorders and ADHD; as well as the effects of stimulants on sleep in ADHD childr
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.