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The article reveals the main results of the study of relevant problems of study of the functional system of movements on the basis of individualization of vocational training of specialists at the higher school. It is appreciated that the essence of the concept of "individualization" is based on modern trends in the stepwise development of the lighting process, methods and forms of pedagogical infusion with the improvement of the individual features of the people. It is emphasized that understanding the mechanisms of individualization helps to identify difficulties in professional training and allows to modify and coordinate the links between the elements of this complex dynamic structure, thus creating the conditions for achieving the desired result. Designed to individualize the intensity of the motivation for the health of the higher education, activating its purposefulness, provides forming of a need in a professional self-improvement. Based on the results, it is concluded that in a broad sense, the individualization of training is: first, the form of interconnection of elements of the educational process, based on a selection of measures to improve training of future professionals, tools and pace of learning and generalization of new information the specified subject, taking into account individual features of applicants of higher education; secondly, a number of educational and methodological activities that provide an individual approach, overcoming pedagogical barriers. It is noted that in the narrow sense, individualization of training is an effective tool to expand the understanding of higher education about the structure, normal and individual development of the human body and its motor functions, study the morpho-functional organization of the musculoskeletal system, assess the functional state of all organs and systems. To further direct investigation of the problem, the development of the evolution of scientific evidence about the formation of professional competencies of future physical therapists, as well as rehabilitation specialists in ambushes of individual vocational training. Keywords: individualization of vocational training, functional system of movements, functional anatomy, specialists, students, educational process.

Modern extremely difficult working conditions encourage teachers to make changes in the theory of pedagogy and the practice of the modern educational process. The concept of the New Ukrainian School envisages an orientation towards learning that will develop critical and productive thinking of schoolchildren, their creative approach to solving emerging problems. In the conditions of modern education, it becomes an objective necessity for the teacher to master and use innovative technologies in his lessons during training. Innovative learning is based on a certain number of technologies, among which there is also a place for problem-based learning. The article substantiates the expediency and investigates the possibility of using elements of problem-based learning in biology lessons as a means of increasing the effectiveness of the lesson in a modern school. 28 students of the 10th grade of secondary comprehensive school in Dnipro took part in the study, which was conducted in three stages. In order to find out the influence of elements of problem-based learning on increasing the effectiveness of the lesson, we used: problem situations, problem questions and tasks that were aimed at increasing the level of mental development of schoolchildren, their ability to independently search for new knowledge and creativity. The level of cognitive activity of students in biology lessons was assessed using the B. Pashnev questionnaire. The analysis of the results shows that at the beginning of the study, both girls and boys mainly had an average level of cognitive activity in class (72%). 18% of students had a low level of cognitive activity, and 10% of students had a high level. After the active use of elements of problem-based learning in lessons, a high level of cognitive activity became characteristic of 14% of students, i.e., the number of children with this level increased by 4%; the average level increased by 5% compared to the previous survey; the low level decreased by 9%. Thus, the elements of problem-based learning that were used to increase the effectiveness of the lesson are justified. It is important to use active learning methods that correspond to the learning content. It is in this way that it is possible to develop in students the ability to independently apply the acquired knowledge in non-standard situations. Key words: problem-based learning, motivational activity, problem situation, problem task, problem questions.

2018). Cytoprotective processes induced by the effect of L-arginin-L-glutamate in rats with experimental pathology of the gastroduodenal zone.The processes of effect of L-arginine-L-glutamate on peroxidation and slime-forming function of the stomach cells, the system of antioxidant defense in the blood, liver and brain tissues of rats with experimental pathology of the gastroduodenal zone have been investigated. The animals were divided into four groups. Group I -control group were rats injected intragastrically through a probe physiological solution. Group II included animals with erosive ulcerative lesions of the gastroduodenal zone. Modeling of the erosive ulcerative lesions was carried out by intragastric administration of medical bile (1 ml/100 g) in combination with immobilization-cold stress for 1 hour at + 4 ºС for a period of seven days. Rats of group ІІІ simultaneously received an intra-abdominal 4% solution of L-arginine-L-glutamate in a dose of 20 mg per 100 g of body weight at the same time as the erosive ulcerative lesions modeling. To clarify the role of NO-ergic mechanism of L-arginine-Lglutamate influence on the quantitative composition of mucins and free radical processes rats in group ІV with erosive ulcerative lesions were injected with non-selective NO-synthase inhibitor, L-NAME (L-NG-nitroarginine methyl ester), at a dose of 1 mg per 100 g at the same time as injections of 4% solution of L-arginine-L-glutamate. The simulation of erosiveulcerative lesions of the gastroduodenal zone in the experimental animals was accompanied by the intensification of lipid peroxidation processes, the imbalance of the antioxidant defense systems and the development of oxidative stress in the blood, tissues of the stomach, liver and brain, which has tissue-specific features. In the blood of the animals, the activation of the enzymatic link of antioxidant defense did not compensate for free radical processes, as a result, the exhaustion of the reduced glutathione pool occurred, and the level of TBA-active products increased both in plasma and in erythrocytes. There was a depression of the enzymes of the antioxidant defense and a decrease in the level of recovered glutathione, indicating decompensating of the liver antioxidant protection systems in the liver tissue of the rats. In the experimental animals , formation of erosive ulcerative lesions was accompanied by destabilization of the oxidation-reducing processes in the brain, which led to the intensification of the lipoperoxidation. In the mucous membrane of the stomach of the experimental animals, the total number of protection factors -secretory mucins with a simultaneous structural change -decreased. The use of L-arginine-Lglutamate reduced the manifestations of oxidative stress in the stomach tissue of animals with experimental pathology and normalized the quantitative and qualitative composition of mucins. In the blood, liver tissues and brain of the rats, L-arginine-Lglutamate injections activated the enzymes of the first anti-radical linkage -superoxid...

АНТИОКСИДАНТНИЙ ЗАХИСТ ТА СКЛАД ГЛІКОПРОТЕЇНІВ СЛИЗОВОЇ ОБОЛОНКИ ШЛУНКА ЗА ЕКСПЕРИМЕНТАЛЬНОЇ ПАТОЛОГІЇ ГАСТРОДУОДЕНАЛЬНОЇ ЗОНИ ПРИ ЗАСТОСУВАННІ L-АРГІНІНУ-L-ГЛУТАМАТУ Л. А. ПОНОМАРЕНКО, завідувач клініко-діагностичної лабораторії, КЗ ''Дніпропетровська обласна дитяча клінічна лікарня'' ДОР''