Oxidative stress is an imbalance between radical-generating and radical-scavenging activity, resulting in oxidation products and tissue damage. This study was aimed to evaluate the status of oxidative stress indices in blood of camels naturally infested with S. scabiei. Forty-seven male camels (Camelus dromedaries) were divided according to the extent of the infested area with Sarcoptes scabiei into four groups, mild (MID, n = 12), moderate (MOD, n = 10), severely infested (SEV, n = 10) and healthy control group (n = 15). Blood was used for determination of red cell count (RBC), hemoglobin (Hb), packed cell volume (PCV), serum nitric oxide (NO(•), a free radical), ascorbate and albumin concentrations, and erythrocytic values of malondialdehyde (MDA, a marker of lipid peroxidation), protein carbonyls (PC, an indicator of protein oxidation), glutathione (GSH) superoxide dismutase (SOD) and catalase (CAT). Decreased levels (P < 0.05) of RBC, Hb, PCV, albumin and ascorbate were noticed in MOD and SEV compared to controls with the lowest values (P < 0.05) in SEV except for ascorbate, where MOD did not differ from SEV. Compared to controls, NO(•) gradually increased (P < 0.05) in MID followed by MOD and SEV, whereas MDA and PC were higher (P < 0.05) in MOD and SEV. PC was higher (P < 0.05) in MOD than SEV. In addition, the antioxidants GSH, SOD and CAT were higher (P < 0.05) in MID and lower (P < 0.05) in MOD and SEV compared to controls. GSH was lower (P < 0.05) in SEV compared to MOD. Besides, Hb was negatively correlated with NO(•) (r = -0.68, P < 0.001), MDA (r = -0.53, P < 0.001) and PC (r = -0.73, P < 0.001). In conclusion, dromedary sarcoptosis is accompanied by a state of oxidative stress process, which increased by increasing the area of infestation, and may contribute to the pathogenesis of the disease.

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A sample of (700) seven hundred out of (3000) three thousand randomly collected livers of sheep and cattle from Mosul abattoir during a biweekly visits of six months period , has been subjected to both grads and histopathological examinations.  Results indicated that parasites induced the highest percen tages of tissue changes in the livers of cattle and sheep, the parasites responsible were Hydatid Cysts and Fasciola gigantica which indicated that Mosul and surrounding areas were endemic with these parasites. Typical cases of liver cirrhosis were recognized in cattle and less in sheep. Mixed infection of mentioned parasites with liver abcesses and hepatic necrosis were diagnosed more frequ ently in sheep than in cattle, a diffuse form of lesbons was round in cattle while the focal from was encountered in sheep.  Congestion and degenerative changes like fatty livers were not seen in cattle but formed a respective percentage (1%) and (1.1%) in sheep. Other conditions were identified like icteric livers , than percentages were and low closely relatd in both species of animals.

treated with oral dose of albendazole. Efficacy of the drug was assessed on the basis of absence of parasitic eggs in the faecal sample, clinical improvement and weight gain. Based on this study, it is now possible to explore the possibility of using strategic treatments for the control of parasitic gastroenteritis in this area.

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