Background: The COVID-19 pandemic presents humanity with an extraordinary challenge. The rapid spread of the virus and the necessity of waiting for effective treatments or vaccines highlights the importance of changing human behaviour to contain the pandemic. Objectives: To assess the knowledge, attitude, and practices of COVID-19 among Benha Health Technical Institute (BHTI) Students. Methodology: This is a cross-sectional study that included 398 undergraduate and complementary education students of Benha Health Technical Institute. The study was conducted using a structured self-administered questionnaire regarding COVID-19. Results: As regard knowledge, the higher percentage of correct answers was for complementary education students in comparison with undergraduates. Regarding attitude, about half of both undergraduates as well as complementary education students showed agreement about the majority of attitude items. With respect to practices, there was low level of practicing the different preventive measures against the disease. Conclusion: Complementary education students had higher level of KAP in comparison with undergraduates.