Adult Swiss albino mice were fed orally with suspensions of a strain of West Nile virus isolated in Nigeria. Most of these mice became sick and died 7 days post feeding and virus was recovered from organs of such infected mice. Histological lesions were observed in some tissues and antibody to the strain of West Nile virus developed in mice that survived infection.
The serological response of puppies from Nigeria to live Flury low egg passage (LEP) rabies vaccine was determined. Two sets of puppies were used: one set from rabies-vaccinated bitches and another set from non-vaccinated bitches. Puppies were vaccinated intramuscularly with Flury LEP strain rabies vaccine and serially bled from the 4th week to the 30th week. Serum rabies virus neutralizing antibodies (VNA) were measured by a modified rapid fluorescent focus inhibition test (RFFIT). Puppies from non-vaccinated bitches responded well to vaccination after the 4th week and through to the 10th week of age, showing a progressive increase in VNA. In contrast, puppies from vaccinated bitches responded well to rabies vaccination only at 10 weeks of age, although detectable maternal rabies VNA and rabies anti-ribonucleoprotein (RNP) antibodies had decreased by 6 weeks post partum.
This report presents six cases of canine transmissible venereal tumour (TVT) in the genital organs with metastasis to extragenital locations. These extragenital sites were the skin, lymph nodes, spleen, tonsils, liver and lung. Foci of metastasis were found in six different organs in one case, two organs in another case and one organ in the remaining four cases. Multiple tumour nodules were, however, found in certain organs such as the skin and spleen. The extragenital tumours were identified as TVT on the basis of their histological similarity to the primary genital tumours. Metastasis appeared to be mainly by lymphatic pathways and by oral implantation. Résumé. Ce rapport présente six cas de tumeur vénérienne transmissible (TVT) dans les organes génitaux avec métastase aux endroits extragénitaux. Ces endroits extragénitaux étaient la peau, les nouds lymphatiques, la rate, les amygdales, le foie et les poumons. Des foyers de métastase ont été trouvés dans six organes différents dans un cas, dans deux organes dans un autre cas et dans un organe dans les quatre cas restant. On a, cependant, trouvé des tumeurs multi‐nodulaires dans certains organes tels que la peau et la rate. Les tumeurs extragénitales ont été identifiées comme TVT en se basant sur leur similarité histologique aux tumeurs génitales primaires. La métastase semblait ětre principalement par voies lymphatiques et par implantation orale. Zusammenfassung. Dieser Bericht stellt sechs Fǎlle dar von ùbertragbar venerischem Hunde‐Tumor (TVT) in den Geschlechtsorganen mit Métastase an extragenitalen Stellen. Dièse extragenitalen Stellen waren die Haut, Lymphknoten, Milz, Mandeln, Leber und Lunge. Herden von Metastasen fand man in sechs verschiedenen Organen in einem Fall, zwei Organen in einem anderen Fall und in einem Organ in den ùbrigen vier Fǎllen. Zahlreiche Tumorknǒtchen (Noduli) wurden jedoch in gewissen Organen wie Haut und Milz gefunden. Die extragenitalen Tumoren waren als TVT identifiziert auf Grund ihrer histologischen ǎhnlichkeit mit den primaren Geschlechtstumoren. Metastasen traten hauptsàchlich durch lymphatische Bahnen und durch orale Einpflanzung ein.
Between March, 1974 and February, 1975, blood smears made from 500 of the dogs brought to the small animal clinic of the University of Ibadan and the state owned veterinary clinic in the same town were stained with Giemsa and examined for blood parasites. Forty‐nine per cent of the dogs carried blood parasites, the commonest of which was Babesia cards. Others were B. gibsoni, Haemobartonella canis, Trypanosoma congolense, Eperythrozoon and Microfilaria. The parasitaemia due to these parasites in the dogs examined was mostly light, although a substantial number of dogs had medium and heavy parasitaemias. No significant difference was found in the susceptibility of the local and exotic breeds to infection with the parasites.
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