The aim was to evaluated anatomical and symptom specific outcome measures of prolapse repair with PROLIFT ® (Gynecare). In this longitudinal prospective observational study we collected data on a total of 85 women with pelvic organ prolapse stage 2 or more. Objective success rate was 85.9% at 6 months respectively. Patients required a blood more 500 ml - 7,1% and need transfusion. The mesh erosion rate or the displacement of the mesh were 3,5%. Vaginal surgery with prolift mesh® is an effective and safe procedure to correct pelvic organ prolapse over one year follow up.
The purpose of our study was the choice of the method with minimal harm to the reproductive health of women with early cervical pathology. We have analyzed the different techniques that can be used for the treatment of CIN or the early stages of cancer. There are sold-knife conization, laser conization, cryotherapy (freezing and destroying abnormal cells), laser vaporization (using a laser to destroy abnormal cells), loop electrosurgical excision procedure (LEEP). All procedures are threatening complications of pregnancy, for example, risk of miscarriage. Method with minimal complications had LEEP, including data on CIN recurrences and complications during pregnancy. Therefore, women who are considering future pregnancies should be counseled about these risks and benefits of procedures.
В течение нескольких лет имеет место дублирование работ, направленных на об наружение наиболее эффективных прог рамм диагностики и лечения опухолей яичников (ОЯ). Разочаровывающие ре зультаты общей выживаемости больных раком яичников (РЯ) после современной стандартной терапии даже при оптималь ной циторедуктивной операции заставля ют искать новые пути совершенствования и индивидуализации лечения. В этом по могают уже известные факторы прогноза, которые подразделяются на несколько больших групп.Опухолевый фактор включает распро страненность, гистологический тип, сте пень инвазии, дифференцировки и плоид ность опухоли.Лечебные факторы можно подразде лить на хирургический, включающий радикальность операции, ее объем и трав матичность, и лекарственный, зависящий от чувствительности опухоли к химио терапии. Для определения прогноза и оценки факторов, влияющих на подбор индивидуального лечения, ретроспективно проанализировано 34 истории болезни пациенток с муцинозными опухолями яичников (МОЯ), имеющих высокий риск развития псевдомиксомы брюшины. Выявили, что МОЯ имеют клинические, биохимические и гистоиммунохимические особенности, позволяющие прогнозировать риск рецидива и индивидуализировать лечение. КЛИНИКО МОЛЕКУЛЯРНЫЕ АСПЕКТЫКлючевые слова: маркеры муцинозных опухолей яичников, раковый антиген (СА 19,9), раково эмбриональный антиген (РЭА). CLINICAL AND MOLECULAR ASPECTS OF MUCINOUS OVARIAN TUMORS: ETIOPATHOGENESIS, INDIVIDUALIZATION OF TREATMENTKedrova AG, Levakov SA, Shablovskiy OR, Wanke NS, Nechaeva OV, Maksimenko TA To determine the prognosis and prognostic factors in series of mucinous tumors of the ovary (MTO) we included 34 patients in our retrospective review. Criteria were defined: 1.centralized his tological review by our expert pathologist; 2. high risk of peritoneal pseudomyxoma or any synchro nous malignant tumor in the abdominal cavity; 3. available data on the management and outcomes of patients. We found specific markers overexpression in mucinous ovarian tumors compared to their normal ovary tissues and serous type ovarian tumors by analysis of serum CA 19,9, CEA and immunohistochemistry. These results suggest that mucinous tumors of the ovary have distinctive cancergenesis and may attribute to the progression of the mucinous ovarian cancer.Key words: markers overexpression in mucinous ovarian tumors, cancer antigen (CA 19,9), can cer embryonic antigen (CEA).
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