The beginning of the military aggression by the Russian Federation induced the suspension of education at all levels. Starting from March 14th, the training has continued in a remote format. But, although all educational institutions had the experience of distance learning, teaching during the war revealed its own features. During the war in Ukraine, health care facilities remain a military target, causing casualties among medical personnel. This, together with medical workers` abduction and migration, resulted in a shortage of medical staff. Under such conditions, the contribution of senior students and higher medical institution graduates was significant. Therefore, the continuation of medical education during the war is of great importance for an effective health care system functioning. The aim. Highlight the experience of distance learning organisation at the clinical department during the war and the problems were discovered during the class. Materials and methods. Classes were held daily with the mandatory synchronous and asynchronous parts, and the organisational component ensured their connection. The asynchronous component was organised by answering an extended clinical case, which included several theoretical questions and five mandatory tasks. To decrease the load for the teacher, the time limit for answering clinical case has been set, and a template of standard comments has been created. In addition, students were required to answer KROK2 tests. The synchronous component of distance learning was implemented using a Google Meet video conference, held daily according to a pre-approved schedule. In order to increase the level of student's communication skills, improve clinical thinking, as well as the practical application of the acquired knowledge, a "clinical" simulation was carried out during each video conference. Due to the pandemic of COVID-19, institutions of higher medical education had a well-established mechanism of the distance learning organisation. However, active hostilities on the territory of Ukraine led to additional obstacles. The lack of sufficient resources to meet the physiological needs limited the students' opportunities to study because, according to A. Maslow, the fulfilment of basic needs is important to an effective cognitive activity. The sound of air raid sirens required interrupting the online part and descending into a bomb shelter. A chronic shortage of basic needs realisation led to a disturbance of the emotional state and consequently hindered the effective processing and memorisation of the material. The absence of stable Internet and being in different time zones also interfered with efficient education. Students' participation in volunteer activities impeded their ability to engage in and concentrate on the educational process. Conclusions. Despite the sudden start of military aggression, institutions of higher medical education quickly switched to distance learning. As in the times of the COVID-19 lockdown, online education consisted of synchronous and asynchronous parts connected through the organisational component. However, active military operations and the constant threat of aerial attacks have created additional obstacles: security issues during the study, emotional state of students and teachers, problems with the Internet, power blackout, and being in different time zones. In addition, students` volunteer activities impeded full engagement in the learning process.

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The purpose of the research was to study the effect of Allium cepa L on the growth processes of the coherent properties of various water sources and samples of distilled and natural water with the electrophysical properties of the original samples transferred to them. Materials and methods. The Kirlian gas-discharge glow of water droplets was recorded on an X-ray film. We used histograms of the luminescence corona brightness, calculated the values of the Euclidean distance for the medians of the heights of the histogram columns and for the differences in the medians in adjacent intervals. The values during of the research were compared with similar parameters of pre-formed samples of images of typical waters (distilled, tap water, from natural sources outside and from the territories of monasteries), as well as water samples with an established type and degree of coherence. The objects of the growth test were onion plants – Allium cepa L. The height of the seedlings, the length of the roots were estimated, and their dry weight was determined. Results and discussion. The identity of the signs of coherence in most samples of electrophysical (energy-informational) copies of water from original sources, the correspondence between the results of the growth test and the properties of water coherence were revealed. There was an increase in the biomass of the test culture when grown on samples with dextrorotatory coherence of water as its degree increased. With levorotatory polarization of water coherence, the biomass decreases with an increase in its degree. The study showed the possibility of transferring the electrophysical properties of various samples of natural water both to distilled water and to other water samples from natural sources. We experimentally demonstrated the possibility of transferring the quantum properties of liquid-phase objects for the preparation and use of biologically active substances in agriculture, biology and medicine without their side effects. Conclusion. Kirlian photography of water can be used as an additional way of express-indication of the physical state of the water basins of the biosphere, including the quality of drinking water by their coherent properties. It is perspective to study the effects of water sources with certain coherent properties on the growth processes of certain plant species and their parts

The purpose of the study was to review the literature on cases of leukemia in healthy people after the COVID-19 infection with a description of our own observation. Materials and methods. 26 literature sources were reviewed and analyzed using the PubMed/MEDLINE database regarding diagnosis of the leukemic process in patients after COVID-19. Analytical and bibliosemantic methods were used in the research. Results and discussion. Many aspects of the COVID-19 infection, especially its complications and long-term health consequences, are still unknown. Various reactive changes in blood tests during COVID-19 have been published. Leukocytosis, leukopenia, neutrophilia, lymphocytosis and lymphocytopenia, thrombocytopenia and rarely thrombocytosis were most often detected. The detected changes were usually not observable in patients. There are reports of leukemia after a recent COVID-19. Therefore, studying the features of the clinical picture and hematopoiesis in such patients during a viral infection, as well as at the initial manifestations of leukemia, is relevant. Costa B. and co-authors report cases of the development of the leukemic process in previously healthy young patients. Patients are aged 31-35 years with normal blood tests, in whom the manifestation of leukemia appeared approximately 2-3 months after COVID-19. The course of COVID-19 was not severe in all. Mild microcytaria was detected in one case of hypochromic anemia. The development of malignant hematological diseases in these patients with an unfavorable prognosis for the course and response to treatment attracts attention. These was T-cell acute lymphoblastic leukemia, myelodysplastic syndrome, acute myeloid leukemia with trigeminal dysplasia in the bone marrow, suggesting previous myelodysplastic syndrome. Nekooghadam S. M. and co-authors presented a case of acute myeloid leukemia in a man after recovery from COVID-19 after 1.5 months. The course of the infection was severe. The blood test showed slight leukocytosis. Manifestations of the described cases of leukemia included clinical gastroenteropathy and anemic syndrome. Two- or three-fold severe pancytopenia and dysplasia were more common in the analysis of bone marrow hematopoiesis. Low blastemia was a feature. Some authors suggest that SARS-Cov-2 plays a role in leukogenesis. The leading role in this is attributed to the imbalance of the renin-angiotensin system caused by the virus, which triggers leukogenesis in several mechanisms. An abnormal immune response to a viral infection can trigger secondary mutational events, contributing to the clinical development of leukemia. In addition to the effect of SARS-CoV-2 on renin-angiotensin system, other mechanisms of the potential development of cancer may underlie it. In particular, COVID-19 has been associated with T-cell exhaustion and activation of oncogenic pathways, including JAK-STAT, MAPK, and NF-kB. The coronavirus non-structural protein stabilizes factors by increasing RCHY1-mediated apoptosis-associated degradation of p53. The case of an acute leukemic process described by us was distinguished by a rapid atypical course, neurological symptoms, pancytopenia in peripheral blood during hospitalization, and a changed linear morphology of blast cells. Conclusion. According to the literature, the leukemic process after a sustained COVID-19 more often has an acute myeloid variant with hematopoietic dysplasia and a severe atypical course. Hematological monitoring of patients who have undergone COVID-19 in the presence of an oncology history or changes in the blood test during recovery from it is necessary. It is advisable to have a control of the hemogram after 2-3 months

The article represents an analysis of the dynamics of the main demographic, clinical, laboratory, and instrumental investigations, final diagnoses of patients who were hospitalized with a diagnosis of acute coronary syndrome without ST segment elevation. A distinctive feature of the work is the recruitment of patients in the same medical institution for different periods of time, which makes possible to trace the dynamics of the clinical profile of patients in the population of Dnipro, a large industrial center of Ukraine. The prevalence of arterial hypertension, chronic heart failure and previous myocardial infarction remained at the same level. In the 2017-2020’s group compared with the 2015’s group, electrocardiographic  manifestations of acute coronary syndrome without ST-segment elevation upon admission were more often detected. Laboratory indicators such as hemoglobin, creatinine and total cholesterol levels remained the same. Another interesting finding is a statistically significant decrease in the number of patients with a reduced glomerular filtration rate according to MDRD (less than 60 ml/min/1.73 m2) in the 2017-2020’s group compared to patients in 2015’s group, although the clinical course of the disease remained practically unchanged. There was a trend towards a worsening of the clinical status and prognosis, namely, increase in the prevalence of atrial fibrillation and diabetes mellitus, increase in the risk of GRACE, as well as increase in the quantity of verified diagnoses of unstable angina, which is most likely associated with the increased use of high-sensitivity troponin. Noteworthy feature is that increase in the quantity of high-risk patients led to an increase in the mean GRACE score.