except for 1 case. No mutation was detected in p53 exons 5 to 8 in tumors with cytoplasmic p53, suggesting that they express wild-type p53. The data indicate that a cytoplasmic accumulation of wild-type p53 in human primary glioblastomas correlates with a certain intermediate lament protein expression, suggesting that it identi es a certain subset of tumors. Neuro-Oncology 4, 171-178, 2002 (Posted to Neuro-Oncology [serial online], Doc. 01-055, April 10, 2002