In a double-blind study, patients with phlebographically proven deep venous thrombosis (DVT) were treated with subcutanous injections twice a day of either unfractionated heparin (UH; n = 27) or low molecular weight heparin (LH; n = 29) for 7 days, and the dose was adjusted until therapeutic range was reached, according to a chromogenic substrate anti-Xa assay. Forty-eight percent of the LH group did not need dose adjustment as compared to 24% of the UH group. During the course of heparin administration, deviation from initial heparin activity was frequent in both groups, but mean activity did not indicate a cumulative effect in either group. There was 1 incidence of pulmonary embolism (LH) and only 1 minor bleeding episode (UH). Half of the patients in both groups were phlebographically improved. We conclude that subcutaneous heparin treatment with UH or LH appears safe and convenient.

In six patients with clinical and electroencephalographic signs of brain death, pituitary hormones such as prolactin, human growth hormone (GH), luteinizing hormone (LH), and thyrotrophin (TSH) were measured in blood close to the demonstration of intracranial circulatory arrest by angiography. In addition, pituitary hormone releasing tests and an insulin test were carried out in two patients. The results showed that no patient had a general decrease in hormone levels, according to their biological half life times, which suggests there still was some function in the hypothalamus and pituitary. This was supported by the results of the stimulation tests. It is concluded that in brain death some basal parts of the brain may still be perfused despite the fact that angiography indicates circulatory arrest in these areas.

Forty-three former players for the National Football Team of Norway were examined clinically and radiologically for degenerative changes in the cervical spine. Compared with men of the same age groups the onset of degeneration was 10-20 years earlier and the frequency of degeneration was significantly higher. Degenerative changes were not especially high in "headers", but this group had a higher frequency of subjective complaints and clinical findings such as reduced cervical movements.

A new method combining selective gas cisternography and computed tomography for the examination of expanding lesions in the cerebellopontine angle cistern is described. Small amounts of gas injected by lumbar puncture can, with proper technique, easily be trapped in the cerebellopontine cistern. Acoustic neuromas protruding into the cistern are visualized as filling defects in the gas. Filling of the internal auditory canal with gas may be demonstrated in normal cases. The possibility of diagnosing intracanalicular tumors is uncertain.