There was made the analysis of wound ballistics of modern expansive bullets in comparison with shell bullets on 25 blocks of ballistic plasticine (ROMA PLASTILINA No. 1, Ballistic Testing Backing Material), made in the USA, in which one shot from an AKS-74 automatic firearm and carbine ZBROYAR Z-10 with an optical sight was fired. The bullet speed was the highest in  5.45x39 caliber cartridge with a V-max bullet. – 1185 m/s, low in the bullet caliber cartridge .308 Win with a bullet SP, – 664 m/s. The difference is significant at the level of significance α=0.05. In terms of the size of the entrance hole, the largest is from the bullet of cartridge .308 Win with a bullet SP – 10.0 cm, the smallest - from the bullet "PS" with a steel core 5.45x39 mm, cartridge sample of the year 1974 (7H6) – 1.2 cm. The difference is significant at the level of significance α=0.05. In the expansive bullet of type "V-Max" of shortgun cartridge of caliber 5.45x39 mm, the size of the entrance hole was 9.1 cm, with asterial shape having radial  gaps and turned edges of ballistic plasticine on the outside. All cartridges with expansive bullets did not have an exit hole after the shot. The dimensions of the formed residual cavity were the largest after firing with .308 Win caliber cartridge with a bullet SP – 25.0x5.0 cm., the smallest – bullet of a military caliber cartridge of 5.45x39 mm (7H6) – 6.0x4.0 cm. The difference is significant at significance level α=0.05. The shape and character of the residual cavity in ballistic plasticine was significant for all expansive bullets, in contrast to the bullet of a military cartridge 5.45x39 mm (7H6), where no such changes are detected. The considerable signs of expansion properties and deformation of the bullet in the form of a "flower of death" were identified in the bullet of caliber cartridge .308 Win with a bullet SP, other bullets with expansive properties showed significant fragmentation, with the location of fragments both in the residual cavity and outside its borders at different distances. Expansive bullets differ significantly at the level of significance α=0.05. The low flight speed of bullets (m/s) of .308 Win caliber cartridges with bullets BTHP and SP is due to their structure, weight, and caliber. Bullet of type V-max with cartridge 5.45x39 mm has the highest speed – 1185 m/s, and due to its design has significant expansive properties. Common to expansive bullets is a entrance hole, the blind nature of the lesion with the presence of a  large residual cavity, which is due to kinetic energy return 114.37 E, J/mm2 inside the object of lesion. Fragmentation of expansion bullets occurs inside an object with fragments located at different distances. A .308 Win caliber cartridge with  SP bullet causes deformation of s bullet by the type of "death flower" causing significant damage.

For the purpose of single-lung ventilation, various methods of lung isolation are used in the world, which is a prerequisite for many thoracic, cardiac and esophageal surgeries. Numerous studies have reported various methods for determining the optimal suitability between the diameter of the tube and the diameter of the left main bronchus for adequate ventilation and gas exchange during operations on the thoracic cavity. However, there is no consensus among anesthesiologists on the choice of tube size for effective lung ventilation and isolation. We have developed a new mathematical formula for determining the appropriate size of the left bilateral luminal endobronchial tube (LDT). The aim of the study was to determine the effectiveness of the developed standardized mathematical formula for determining the appropriate size of LDT for use in thoracic anesthesiology. The study was performed on 192 patients with diseases of the thoracic cavity (esophagus, lungs, mediastinum), operated on in the thoracoabdominal department of the Shalimov National Institute of Surgery and Tranplantology. A retrospective comparison group – 96 patients after thoracic surgery, which used the choice of LDT size according to the well-known Slinger method “according to the patient’s height”. The study group consisted of 96 patients after thoracic surgery, in which the choice of the size of the bifurcated endobronchial tube was used according to the developed method (according to the formula that evaluates morphometric indicators of height, sex and diameter of the left main bronchus). The application of the proposed method reduces (p = 0.001) the risk of pulmonary complications, HR = 0.39 (95 % CI 0.22-0.70) compared to traditional methods. The risk decreased 2.5 times.

Annotation. Pulmonary complications are a key problem in the postoperative period in patients with diseases of the thoracic cavity. They are characterized as the main factors of longer recovery and hospital mortality. The aim of the study was to compare the indicators of oxygenation of patients and the number of postoperative pulmonary complications after thoracic surgery, depending on the method used to select a dual endobronchial tube. The study was performed on 192 patients with diseases of the thoracic cavity (esophagus, lungs, mediastinum), operated on in the thoracoabdominal department of the Shalimov National Institute of Surgery and Tranplantology. A retrospective comparison group – 96 patients after thoracic surgery, which used the choice of DLT size according to the well-known method of Slinger “according to the patient's height”. The study group consisted of 96 patients after thoracic surgery, in which the choice of the size of the dual endobronchial tube was used according to the developed method (according to the formula that evaluates morphometric indicators of height, sex and diameter of the left main bronchus). EZR v 1.54 statistical software was used for statistical calculations. (graphical user interface for statistical software R version 4.0.3, R Foundation for Statistical Computing, Vienna, Austria). Pulmonary complications developed in 33 (34.4%) patients of the control group and in 13 (13.5%) patients of the study group, the difference was statistically significant, p=0.001. One-factor analysis revealed a link between the risk of complications and the indicators method, sex, PaCO2, PaO2. For the study group, the risk of complications is lower (p=0.001), BP=0.30 (95% CI 0.15-0.61) compared with the control group. The risk of complications for men is higher (p=0.048), BP=2.33 (95% CI 1.01–5.37) compared to women. An increase in the risk of complications with an increase in PaCO2 (p<0.001), BP=1.34 (95% CI 1.21-1.49) with an increase in the indicator by 1 unit, respectively. With increasing PaO2, the risk of complications decreases (p<0.001): BP=0.96 (95% CI 0.94-0.98) – with increasing 1 unit. Thus, the application of the proposed method in comparison with the traditional method reduces (p=0.001) the number of postoperative pulmonary complications by 2.5 times (from 34.4% to 13.5%).

Esophageal cancer remains one of the most common cancers with a high mortality rate worldwide. A certain problem when treating the esophageal cancer is the highly traumatic surgery, a significant number of post−surgery complications from esophagogastroanastomosis and severe postoperative pain. Therefore, there is a need for new developments and techniques for the formation of esophagogastroanastomosis to minimize post−surgery complications. To reduce the number of postoperative anastomotic complications and improve the pain control in patients after esophageal resection, a study was conducted that included 60 patients with esophageal cancer and cardioesophageal transition. We compared two methods of esophagogastroanastomosis formation: intussusception mechanical and circular mechanical, as well as those of postoperative anesthesia, namely, a combination of thoracic paravertebral blockade and thoracic epidural anesthesia using only thoracic epidural anesthesia. Due to our findings the effectiveness of the proposed intussusception mechanical anastomosis was proven, which allowed to significantly reduce the frequency of endoscopically detected reflux esophagitis by 1.5 times at the end of the one year follow−up observation. It is established that anesthesiological support of postoperative anesthesia during surgery for malignant diseases of the esophagus using combined postoperative analgesia (thoracic paravertebral blockade and thoracic epidural anesthesia) reduces the endocrine−metabolic response in men, generally makes it possible to prevent the development of post−surgery complications. Key words: esophageal cancer, gastroenteroanastomosis, thoracic epidural block, thoracic paravertebral anesthesia, cardioesophageal junction cancer.

Annotation. Surgical interventions for diseases of the thoracic cavity are one of the most invasive surgical procedures, which are often accompanied by postoperative complications, which increase mortality, prolong hospital stays, require additional costs and correlate with poor long-term survival. However, respiratory complications remain the most common of non-surgical complications and their frequency varies from 13 to 38%. So far, several studies have shown that respiratory dysfunction is an independent risk factor for postoperative pneumonia. The aim – investigate whether it is possible to use spirometric lung age to predict the occurrence of postoperative pneumonia after thoracic surgeries. The study was performed on 192 patients with diseases of the thoracic cavity (esophagus, lungs, mediastinum), underwent surgery in the thoracoabdominal department of the Shalimov’s National Institute of Surgery and Transplantation. Statistical software EZR v.1.54 was used for statistical calculations (graphical user interface for statistical software R version 4.0.3, R Foundation for Statistical Computing, Vienna, Austria). We found a very strong association between the risk of developing pulmonary complications and the age of the lungs, AUC=0.97 (95% confidence interval from 0.94 to 0.99). When choosing the optimal point for predicting the risk of pulmonary complications obtained: Lung age critical = 99.6 years. Thus, at Lung age >99.6 years, the development of postoperative pulmonary complications is predicted. At Lung age <99.6 years, the absence of postoperative pulmonary complications is predicted. When choosing this decision point, the sensitivity is 93.5% (82.1-98.6%), specificity – 95.9% (91.3-98.5%). Therefore, spirometric age of the lungs was associated with the incidence of postoperative pulmonary complications in patients undergoing surgery for thoracic disease. This parameter deserves attention as a predictor of the probability of developing postoperative pneumonia after thoracic surgeries and can help in assessing the state of respiratory function of patients.