Acinetobacter baumanii is an opportunistic bacterium that causes widespread nosocomial infections and tends to be multi-resistant to most of antibiotics. Tigecycline is a well-known antibiotic that possesses a wide-range of activities and is very active Tujuan kajian ini adalah untuk menilai kesan dan gabungan antibiotik imipenem dan tigecycline terhadap A. baumanii rintang-karbapenem (CRAB). Kepekatan perencatan minimum (MIC) ditentukan dengan menggunakan kaedah E-test. Teknik papan penyemak mikrokaldu digunakan untuk menentukan kesan imipenem dan interaksinya dengan tigecycline dengan mendapatkan nilai indeks kepekatan rencatan berperingkat (FIC). Ujian masa membunuh (TK) telah dijalankan untuk mengenal pasti kesan sinergi apabila kedua-dua imipenem dan tigecycline digunakan terhadap strain CRAB. Hasil ujian menunjukkan bahawa semua strain A. baumanni memberi nilai imipenem MIC sebanyak 32 μg/mL. Gabungan imipenem dan tigecycline menunjukkan kesan tambahan (FIC> 0,
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