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Bone infarction involving the orbit in sickle cell disease is not common. Bilateral orbital infarction in a previously undiagnosed sickle cell hemoglobinopathy has not been previously reported. In this report, we present a case of an 11-year-old previously undiagnosed sickle cell disease Nigerian girl with severe acute bilateral orbital infarction and retinal detachment to highlight that hemoglobinopathy induced orbital infarction should be considered in African children with acute onset proptosis with or without previous history of sickle cell hemoglobinopathy.

A total of 48 samples of maize-based gruels, used as weaning food for children, were taken daily from hospital meals and from patients' mothers while their children were on admission at the Wesley Guild Hospital, Ilesha, Nigeria. These samples were analysed for aflatoxins and ochratoxin A. Twelve samples (25%) were positive for aflatoxins (concentration range 2-19,716 pg/g) but only four (8%) were positive for ochratoxin (concentration range 142-6516 pg/g). In the majority, the concentrations were relatively low, only two having aflatoxin and one ochratoxin A levels greater than 1000 pg/g. It is concluded that, unlike aflatoxin, ochratoxin A contamination is unlikely to present a major health hazard to the newly weaned child in this area of Nigeria.

Background: Breastfeeding is the ideal form of nutrition for the healthy growth of infants, and it reduces the risk of malnutrition and several childhood morbidities. Objectives: To assess the breastfeeding practices of mothers and the relationship between these practices and the nutritional status of their children. Methods: It was a descriptive, hospital-based, cross-sectional study that involved children aged six to 24 months in Ilesa, Osun State, Nigeria. Socio-demographic characteristics and breastfeeding practices were documented, anthropometric measurements were obtained, and nutritional status was determined for the children. Underweight, stunting and wasting were defined as z-score < -2 for the weight-for-age, length-for-age and weight-for-length, respectively. A child was taken to be undernourished if any of underweight, stunting or wasting was present. Results: Fifteen (3.6%) of the 420 children studied had mixed feeding from birth, while 273 (65.0%) were exclusively breastfed for six months. Two hundred and sixty-eight (63.8%) of them were still breastfeeding at the time of the study, while 152 (36.2%) had stopped breastfeeding. Nearly one-quarter (103/420; 24.5%) of the children were undernourished. A significantly lower proportion of children who had exclusive breastfeeding were undernourished, compared to those who were not exclusively breastfed (p = 0.033). Exclusive breastfeeding was independently associated with reduced odds of undernutrition (OR = 1.62, 95% CI = 1.02-2.57, p = 0.039). Conclusion: Exclusive breastfeeding for six months significantly reduces the risk of undernutrition among young children.

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