No abstract

We did not find support for a visual vs. spatial dissociation in recognition memory. Performance impairment in the visual-spatial domain parallels the increase in working memory (WM) load or in the executive demands of the task. Possible neurobiological implications of the observed performance on the CANTAB tasks are also considered.

In this study, relations between emotional resonance responses to another's distress, emotion regulation, and self‐other discrimination were investigated in infants three‐, six‐, and nine‐months‐old. We measured the emotional reactions to the pain cry of a peer, along with the ability to regulate emotions and to discriminate between self and other body movements. We found evidence that infants do regulate their emotional resonance responses to another's distress. This relation is age specific, with younger infants using more primitive self‐soothing behaviors, while in older participants attentional based strategies relate to affect sharing reactions. Only nine‐month‐old infants have shown self‐other differentiation abilities, and these were significantly connected to their emotions in response to a peer's distress. These findings have implications for our understanding of early empathy development.

The present study examined the associations between attentional biases to threat, attentional control and anxiety in a sample of children aged 9 to 14. It was hypothesised that the association between attentional biases toward threat and anxiety might be stronger when the ability to control attention is reduced. The study employed pictures of neutral, happy and angry facial expressions as they have greater ecological value compared to words. Children completed a dot-probe task measuring attentional biases toward such stimuli. They also completed the Spence child anxiety scale for anxiety symptoms and, for attentional control, the child version of the attention control scale measuring the ability to focus and shift attention. Results of a hierarchical regression analysis showed that attentional control significantly explained anxiety. Furthermore, the interaction between attentional control and attentional biases significantly explained anxiety level. These results indicate that attentional control moderates the relation between attentional biases toward threatening facial expressions and anxiety in children. Additionally, a discussion about a possible protective role of attentional control is provided.

Despite the circumstantial and sometimes equivocal support, the hypothetic involvement of aluminum (Al) in the etiology and pathogenesis of Alzheimer's disease (AD) has subsisted in neuroscience. There are very few other examples of scientific hypotheses on the pathogenesis of a disease that have been revisited so many times, once a new method that would allow a test of Al's accumulations in the brain of AD patients or a comparison between Al-induced and AD neuropathological signs has become available. Although objects of methodological controversies for scientists and oversimplification for lay spectators, several lines of evidence have strongly supported the involvement of Al as a secondary aggravating factor or risk factor in the pathogenesis of AD. We review evidence on the similarities and dissimilarities between Al-induced neurofibrillary degeneration and paired helical filaments from AD, the accumulation of Al in neurofibrillary tangles and senile plaques from AD, the neuropathological dissociation between AD and dialysis associated encephalopathy, and the epidemiological relations between Al in drinking water and the prevalence of AD. We also critically analyze the prospects of Al-amyloid cascade studies and other evolving lines of evidence that might shed insights into the link between Al and AD. The message between the lines of the following article is that the involvement of Al in the pathogenesis of AD should not be discarded, especially in these times when the amyloid dogma of AD etiology shows its myopia.