Numerous studies done on some parts of Napoleona imperialis plant extracts but there is still paucity of information on the proximate composition and nutritive values of Napoleona imperialis stem bark. Objective: This is to evaluate the proximate composition, vitamins, micro and macro elements of Napoleona imperialis stem bark. Methods: Determination of proximate, composition, vitamins, micro and macro elements of Napoleona imperialis stem bark was done using standard methods. Results: This study showed that Carbohydrate had the highest concentration of 59.540% followed by the ash content which was 12.768%. Potassium was found in the highest concentration of 8.246mg/kg followed by Sodium which was 5.853mg/kg. Also, magnesium had 3.497mg/kg followed by selenium of 2.701mg/kg and Calcium of 1.373mg/kg respectively. The least concentration of the mineral contents were found in Iron which had 0.076mg/kg, followed by Aluminium and Copper which were 0.075 mg/kg and 0.072 mg/kg respectively. The stem bark showed the absence of concentration of Tin, Cobalt, Lead, Manganese, Chromium and Vanadium. Vitamin A had a concentration of 5.315mg/kg, Vitamin B1 showed a concentration of 10.920mg/kg, Vitamin B2 showed 0.315mg/kg, Vitamin B3 with 5.430mg/kg, Vitamin B6 with 4012.500mg/kg, Vitamin B12 with 0.355mg/kg, Vitamin C with 1.358mg/kg and Vitamin E with 4.213mg/kg. Conclusion: The present study showed the presence of antioxidant properties and vitamin B complex with other nutritive values. This data indicates that Napoleona imperialis stem bark constitute nutritive ingredients, minerals, vitamins and antioxidants. This justifies the claimed use of the stem bark in the management of certain ailments.