This study investigated the effect of short term aerobic exercise on lipid profile and myoglobin levels in apparently healthy students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria. A total of 60 apparently healthy young students aged between 18-40 years were randomly selected for the study. They were rested for a period of two weeks after which they were subjected to football exercise for 30 minutes (3 times) in a week for a period of 3 weeks. The demographic and anthropometric data of subjects were obtained using a well-structured questionnaire. Their blood pressures reading were obtained also. Thereafter, 5mls of baseline (day 0) and post-exercise (day 21) blood samples were collected from each subject before the commencement and at the end of the exercise on the last day of the training into a plain container for estimation of biochemical parameters (TG, TC, LDL, HDL, Myoglobin levels) respectively using standard methods. Data obtained were statistically analysed by unpaired student t-test and Pearson r correlation. The result showed that the mean serum levels of TG (1.41±0.60 vs 1.04±0.43) TC (5.22±0.98 vs 4.41± 0.90), LDL (3.92±0.99 vs 3.36±0.92) as well as myoglobin (16.04± 4.64 vs 13.38±5.21) and DBP (75.16±10.54 vs 68.59±8.57) were significantly decreased, whereas, there was a significant increase in the mean serum level of HDL (0.83± 0.30 vs 0.95±0.28) and SBP (114.69±9.21 vs 131.48±12.84) in subjects after exercise when compared to before exercise (p<0.05). However, the mean BMI of the subjects remained the same before and after exercise (p>0.05). Therefore, short term moderate intensity aerobic exercise could be of importance in prevention and management of cardiovascular disease.Key Words: Short Term Aerobic Exercise, Football Training, Lipid Profile, Myoglobin, Apparently Healthy Students, Nnewi Campus. IntroductionThe word exercise is derived from the latin word -EXERCITIUM‖ which means to train. Exercise is a process in which energy stored as chemical compound is transformed into mechanical and heat energy (Nevell et al., 1989). Exercises are generally grouped into three types depending on the overall effect they have on the human body:
This was a cross sectional study designed to evaluate the cluster of differentiation 4(CD4) count and hematological indices in HIV serodiscordant partners in Jos, Nigeria. A total of 20 Serodiscordant HIV couples (40 patients) and 20 non HIV couples (40 controls) aged between 18 and 49 years were included in the study. Each participant provided a 5ml venous blood sample that was collected into EDTA containers for the analysis of the CD4 count and hematological indices. The following blood parameters were measured using a three pack full blood count autoanalyzer: white blood cell (WBC), red blood cell (RBC), hematocrit/packed cell volume (HCT/PCV), hemoglobin (HB), platelet count (PLT), lymphocyte, neutrophil, and mixed cell (NUE/NAC) count. The CD4+-T cell was measured using flow cytometry. The results showed that the mean RBC count, platelet count, mixed cell count (Nue/Nac), HCT/PCV and HB levels, as well as the CD4-T cell count, were all significantly lower while the mean age was higher in the HIV serodiscordant test group compared to control group (p<0.05) respectively. The mean neutrophil, lymphocyte, and WBC counts in the HIV serodiscordant test group did not statistically differ from those in the control group (p>0.05). The HB, HCT/PCV, RBC, lymphocyte, and CD4 counts in the female HIV serodiscordant test group were statistically significantly lower than those in the female control group (p-value=0.008; 0.002; 0.000, 0.008, 0.000), respectively. The male HIV serodiscordant test group had statistically significantly lower mean neutrophil and CD4 counts than in the male control (p-value=0.000; 0.012) respectively. The female HIV seropositives had a statistically significantly lower mean RBC count, Hb, PCV, and CD4 count (p-value =0.000; 0.037, 0.005 and 0.000) than in female control respectively. Also, the female HIV exposed seronegatives had statistically significantly lower mean CD4 count (p-value =0.000) and Hb (p-value =0.037) levels than in female control while the male HIV seropositives had statistically significantly lower CD4 count compared to male control (p-value =0.000). This study has revealed significant changes in CD4-T cell count and hematological indices in HIV serodiscordant couples, which calls for an urgent interventional strategy to prevent the potential anemia, leucocytopenia, and weakened immunity that may result in both HIV seropositives and seronegative exposed couples.
Dyslipidemia has grown to be a significant global public health issue particularly in developing nations like ours, as a result of rising trends in dietary habits, physical inactivity, and obesity, which each play essential roles in the development of cardiovascular diseases. The purpose of this cross-sectional study was to determine the prevalence of dyslipidemia among undergraduate students at Nnamdi Azikiwe University in Nnewi. Two hundred (200) students between the ages of 18 and 30 who appeared to be in good health were selected at random. After that, each participant provided a fasting blood sample of five milliliters (5ml) for the evaluation of serum total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) using standard laboratory techniques. Additionally, the body mass index (BMI) and the systolic and diastolic blood pressure readings were calculated. 44 percent of participants were males and 56 percent were females, with an average age of 22.41 ±1.68 years. While 3% of the participants were underweight, 27% of them were overweight, and 6% were pre-obese, the majority of them (64%) had a normal BMI. Three percent (3%) of the participants had pre-hypertension, whereas 97% of the participants had normal blood pressure. The prevalence of hypercholesterolemia, hypertriglyceridemia, low HDL-C, and high LDL-C among the participants, as defined by the World Health Organization, was 39.5%, 26.5%, 4%, 12.5%, and 16.5%, respectively. SBP Vs DBP, DBP Vs Weight, DBP Vs BMI, Weight Vs BMI, TC Vs TG, TC Vs HDL, and TC Vs LDL all had significant positive correlations (p<0.05) while SBP Vs TG, SBP Vs HDL, and TC Vs LDL all had significant negative correlations (r=-0.148, p=0.036, and r=-0.203, p=0.004). The female sex was strongly related with dyslipidemia (48.2%), whereas the male sex was not (28.4%). As a result, there is a pressing need to educate the public about the essential changes in food habits and overall lifestyle to maintain cardiovascular health.
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