Abstract. This study evaluated the relationships between national productivity, life happiness, and cultural dimensions in a global framework. The purpose of the study originated from the continued quest for fuller explanations behind persistent differences in international productivity performance, together with the recent worrisome productivity growth deceleration observed in multiple of the world's key economies. Based on applying multivariate regression analysis and hypotheses testing, it was found that the study's omnibus null hypothesis, all four main null hypotheses were rejected in favor of their alternative hypotheses. The results suggested that globalization-impacted businesses seeking to optimize their productivity performance could capitalize on their human factor allocations drawing on the energy of life happiness and certain cultural dimensions-particularly individualism and power distance, either singularly or in combination with other explanatory variables. Implications and further research recommendations for enhancing the understanding of and improving productivity outcomes in a globalizing economy were also provided.