Because dental fluorosis in the United States and other nations without high levels of naturally-occurring fluoride is mild or very mild, with little impact on OHRQoL, dental professionals should emphasize the appropriate use of fluorides for caries prevention and preventing moderate/severe fluorosis.

Because of the high incidence of early childhood caries (ECC), a longitudinal study to identify risk factors from the prenatal period to the child's first birthday among 9- to 18-month-old children was conducted with negative binomial modeling. Overall, 495 children had dental examinations at ages 9, 12, and 18 months. Mothers were interviewed during the 2nd trimester of pregnancy and when the children had dental examinations. The highest incidence of caries was found among children who were born to mothers with >or= 10 decayed teeth and who never received calcium supplements during pregnancy, and children who were not fed supplementary foods at age 3 months, had sweet-tasting foods at 5 months, started snacking at 5 months, had sugary snacks, had soft drinks, and did not have their teeth brushed daily at 9 months. Thus, prenatal care and child-rearing-practices during and after birth are important risk factors for the incidence and incremental rate of ECC.

An extremely high caries-affected rate was found among the study children even before the age of 18 months. The buccal surface of the maxillary incisors was the most affected. The teeth acquired caries at 3-6 months after initial eruption and carious lesions developed continuously over time.

Dental caries is a common disease in children of all ages. It is desirable to know whether children with primary, mixed and permanent dentitions share risk factors for cavitated and non-cavitated caries. Objective To assess the longitudinal associations between caries outcomes and modifiable risk factors. Methods One hundred and fifty-six children in the Iowa Fluoride Study met inclusion criteria of three dental examinations and caries-related risk factor assessments preceding each examination. Surface-specific counts of new non-cavitated caries and cavitated caries at the primary (Exam 1: age 5), mixed (Exam 2: age 9) and permanent (Exam 3: age 13) dentition examinations were outcome variables. Explanatory variables were caries-related factors, including averaged beverage exposure frequencies, toothbrushing frequencies, and composite water fluoride levels collected from 3–5, 6–8, and 11–13 years, dentition category, socioeconomic status and gender. Generalized linear mixed models (GLMMs) were used to explore the relationships between new non-cavitated or cavitated caries and caries-related variables. Results Greater frequency of 100% juice exposure was significantly associated with fewer non-cavitated and cavitated caries surfaces. Greater toothbrushing frequency and high SES were significantly associated with fewer new non-cavitated caries. Children had significantly more new cavitated caries surfaces at the mixed dentition examination than at the primary and permanent dentition examinations. Conclusions There were common caries-related factors for more new non-cavitated caries across the three exams, including less frequent 100% juice exposure, lower toothbrushing frequency and lower socioeconomic status. Less frequent 100% juice exposures might be associated with higher exposures to several other cariogenic beverages.