Drone technology has linked up several opportunities to enable direct connection with the medical consumable donors to receive request through mobile phone communication and deliver medical consumables via Drone device. The recent development in autonomous air navigation and implementation of Drones into mainstream geographical ecosystem have been recognized for adoption in healthcare emergency responses. At the center of the innovation is the Internet of Things (IoT) technology which had necessitated advanced mission specification for Drones to operate beyond visually line of sight (BVLOS) in responding to classified healthcare assignments. The use of Drones in the healthcare management, welfare support, emergency responses and health risk management was investigated in the selected country of the Central East Africa (Rwanda). The research discovered a system of dynamic connection between the tiers of governments in active partnership with the private sector initiative to exploit Drone technology innovation to improve healthcare service delivery up to the grass root level with an outstanding productivity. The article evaluated Africa's involvement in the society healthcare extreme automation using Drone technology capabilities and deliberated on the possibilities and benefits for implementation and adoption into the national healthcare sector in Nigeria. The paper concluded that future implementation of the research will accomplish the digital health demands of Nigeria government, public and private sector health maintenance to guarantee sustainable healthcare investment and effective healthcare service delivery.