Background and objective: The re-emergence of Transfusion Transmissible Infections (TTIs) and Human Immunodeficiency Virus (HIV) through allogeneic blood transfusion has made the subject of autologous blood transfusion to begin to gain adequate attention globally in recent times. This study aimed at enlightening the public on the importance of Autologous blood transfusion as a strategy in curbing HIV, TTI and allogeneic blood transfusion reaction in sub-saharan Africa where poor screening of blood contributes to their spread. To ascertain the suitability of autologous blood transfusion as a safe blood transfusion strategy, the whole essence of which is to achieve better quality of care for our patients. Methodology: The study was divided into 2 parts, one was questionnaire-driven and the other was on the use of Autologous blood transfusion.A total of 40 patients (30 of whom were HIV sero-positive while 10 were HIV sero-negative) aged between 19-55years were randomly recruited for this study in the