Sociological investigations of economic exchange reveal how institutions and social structures shape transaction patterns among economic actors. This article explores how interfirm networks in the U.S. venture capital (VC) market affect spatial patterns of exchange. Evidence suggests that information about potential investment opportunities generally circulates within geographic and industry spaces. In turn, the circumscribed flow of information within these spaces contributes to the geographic-and industry-localization of VC investments. Empirical analyses demonstrate that the social networks in the VC community-built up through the industry's extensive use of syndicated investing-diffuse information across boundaries and therefore expand the spatial radius of exchange. Venture capitalists that build axial positions in the industry's coinvestment network invest more frequently in spatially distant companies. Thus, variation in actors' positioning within the structure of the market appears to differentiate market participants' ability to overcome boundaries that otherwise would curtail exchange.

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A large body of work argues that scientific research increases the rate of technological advance, and with it economic growth. The precise mechanism through which science accelerates the rate of invention, however, remains an open question. Conceptualizing invention as a combinatorial search process, this paper argues that science alters inventors' search processes, by leading them more directly to useful combinations, eliminating fruitless paths of research, and motivating them to continue even in the face of negative feedback. These mechanisms prove most useful when inventors attempt to combine highly coupled components; therefore, the value of scientific research to invention varies systematically across applications.

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