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The prospects of using biopolymer nano-containing films for wound healing were substantiated. The main components of biopolymer composites are gelatin, polyvinyl alcohol, glycerin, lactic acid, distilled water, and zinc oxide (ZnO) nanoparticles (NPs). Biopolymer composites were produced according to various technological parameters using a mould with a chrome coating. The therapeutic properties of biopolymer films were evaluated by measuring the diameter of the protective effect. Physico-mechanical properties were studied: elasticity, vapour permeability, degradation time, and swelling. To study the influence of technological parameters of the formation process of therapeutic biopolymer nanofilled films on their therapeutic and physico-mechanical properties, the planning of the experiment was used. According to the results of the experiments, mathematical models of the second-order were built. The optimal values of technological parameters of the process are determined, which provide biopolymer nanofilled films with maximum healing ability (diameter of protective action) and sufficiently high physical and mechanical properties: elasticity, vapour permeability, degradation time and swelling. The research results showed that the healing properties of biopolymer films mainly depend on the content of ZnO NPs. Degradation of these biopolymer films provides dosed drug delivery to the affected area. The products of destruction are carbon dioxide, water, and a small amount of ZnO in the bound state, which indicates the environmental safety of the developed biopolymer film.

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Background. Restoring large defects with proximal caries extending below the cemento-enamel junction and cavity margins located beneath the gingival tissues represents a very common clinical situation. The aim of this article is to propose a clinical classification of the localization subgingival margins of cavity.Material and methods. Diagnosis is carried out by periodontal probe perpendicular to the long axis of the tooth in the deepest point of the cavity’s margin. To describe the localization subgingival margins of cavity we use exponent which value is equal to the distance (integer number expressed in millimeters) of the level of epithelial attachment to the margin of the cavity. Three periodontal examiners, with >10 years of periodontal practice, were required to attend a calibration session aimed at the validation of the proposed classification. Results. The intrarater and interrater agreement among the localization subgingival margins of cavity: for intrarater agreement ranged from 0.74 to 0.95 (almost perfect agreement), whereas interrater agreement ranged from 0.26 to 0.59 (moderate agreement).Conclusions. The classification the localization subgingival margins of cavity is useful for reaching a more precise diagnosis.

In the problem of solving diagnosis and treatment of hard tissue defects, a significant role is played by the choice of tactics for dental treatment of tooth decay. This work was aimed at studying the problem of diagnosis and systematization of hard tissues defects, that will contribute to the objectification of diagnostic and therapeutic approaches in dental treatment of patients with this disease. The objective of the research was to develop an anatomical and functional systematization for differentiated evaluation of tooth defects, as a basis for the application of differentiated diagnostic and therapeutic approaches to dental treatment of hard tissue defects. Materials and methods. For differential assessment of the extent of tooth defects and precise estimation of the strength of the composition “tooth-restoration”, we conducted   mechanical and mathematical modeling of contact interaction of restoration with dental tissues. We conducted anthropometric studies of all types of cavities of different groups of teeth as well.  Results. As a result of the study, there was proposed the systematization of hard tissues defects – location of defects, occlusive load, extent of defects/ depth of decay. The algorithm for choosing the method of treating hard tissues defects that is based on the systematization of location of defects, occlusive load, extent of defects/ depth of decay and may serve as a selection criterion for the treatment of such pathologies was offered. Conclusions. The proposed systematization filled the obvious gap in academic ideas of hard tissue defects, suggested the prospect of reaching a consensus on differentiated diagnostic and therapeutic approaches in treatment of patients with this disease building the methodological “bridge of continuity” between therapeutic and orthopedic dentistry in the field of hard tissue defect treatment.