The aim: To find solutions for the ecological problems of epidemics danger to acute respiratory infections, especially coronavirus infections, during the organization of mass sporting events by establishing the features of its development and providing epidemiological measures to reduce the negative impact of epidemics for human health and activities, including athletes at both national and international levels. Materials and methods: The methodological basis of this study is general and special scientific methods: dialectical, analysis and synthesis, synergism, historical and legal, formal and logical, systematic and structural, comparative and legal, formal and legal. Empirical data were scientific works, international regulations, EU legislation, United States and other countries. Conclusions: The conclusions that the organization of mass sporting events must take into account the epidemiological situation of the disease in acute respiratory infections primarily on coronavirus infection at the national level to ensure contact with the institutions of the public health national system, use data “Hazard determination and risk assessment systems” (HDRAS) to determine the risk degree of infectious diseases, to conduct timely observation activities.