The article presents the results of a review and analysis of the current state of scientific and methodological support for regional freight transportation. An analysis algorithm was formed, a general description of the most interesting and relevant studies in the area under consideration was made. Dissertation studies in the field of water transport operation and a number of scientific publications have been studied. With regard to regional freight transportation, key features, available developments in scientific and methodological support are indicated, as well as shortcomings, problematic and insufficiently covered issues. Based on the systematization of the results of the reviewed sources, conclusions were made about the most promising areas of further studies, not taken into account or not studied at the moment areas.