The problem of road traffic injuries is one of the prioritized social, medical and technological problems all over the world. The timeliness of medical care provision is of great social and economic importance. In recent years, more attention is paid to the development and improvement of drug provision, which is essential in saving lives of victims in road accidents (road accidents). The aim of our study is the development of new approaches to needs identification and creation of balanced drugs list for provision emergency medical care to victims of road traffic accidents. Methods. A visualization framework, allowing to solve the task, is the development of an intellect card "Drug Provision of Victims in Road Traffic Accidents" which makes it possible to systematize and summarize the large content of research related to planning and identification of needs. As s result, the efficiency of financial resources disbursing increases, the time for the drugs systematization and the medical standards analysis reduces. The results. The intellect card consisting of four stages: the problem study of medical assistance organization to the victims of road traffic accidents, analysis of drugs efficient use in providing medical assistance, efficient choice of drugs, method development of requirement estimation in drugs and financial resources was created. Conclusions. The results of the intellect card creation pointed necessity and relevance of new drugs list formation, regulated drug provision to the victims of road traffic accidents. Organizational steps and work criteria with the standards of rendering emergency medical care, requirement estimation in necessary medications were proposed.
AIM: To identify and describe micro- and ultrastructural thermally induced changes in Bakers cyst wall associated with the duration of unidirectional uniform heating at 70C. MATERIALS AND METHODS: We took one full-thickness fragment from each of the 15 Bakers cysts excised during the operation and divided each fragment into four parts: one was used as a control sample, and the remaining three fragments were placed with the synovial membrane on a thermostat heated to 70C, with exposure times of 60, 120, and 180 seconds. We used light-optical and electron microscopes for the histomorphological examination of the samples. RESULTS: Two layers of Bakers cyst wall were identified: inner (synovial) and outer (fibrous). In samples exposed to heat for 60 seconds, the synovial layer was undamaged. In samples exposed to heat for 120 seconds, thermal damage to the cells of the synovial layer and underlying collagen fibers of the fibrous layer was evident. With a heating duration of up to 180 seconds, histomorphological examination revealed signs of damage reaching the middle of the fibrous layer, and signs of deep disorganization of the collagen fibers of the cyst wall were determined at the electron-microscopic level. DISCUSSION: Using light microscopy of intact sections of the cyst wall, we, like other researchers, identified two layers (synovial and fibrous) of different densities, with blood vessels passing through them. The performed experiment suggests that a clinically significant result using Bakers cyst thermotherapy is achieved when spreading the zone of irreversible coagulation beyond the middle of the fibrous layer of the cyst wall. This, in turn, guarantees damage to the capillary network that provides trophism and proliferation of synoviocytes. The proposed hypothesis corresponds to the paradigm of similar studies on the coagulation of cysts of other localizations. CONCLUSION: The obtained results of the light-optical and electron-microscopic examination of Bakers cyst wall fragments indicate direct dependence of the depth of thermal coagulation on the duration of heating.
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