Purpose [18F]-2-Fluoro-2-deoxy-D-glucose PET/CT (FDG PET/CT) is a sensitive and quantitative technic for detecting inflammatory process. Glucose uptake is correlated with an increased anaerobic glycolysis seen in activated inflammatory cells such as monocytes, lymphocytes, and granulocytes. The aim of the study was to assess the inflammatory status at the presumed peak of the inflammatory phase in non-critically ill patients requiring admission for COVID-19. Methods Patients admitted with COVID-19 were prospectively enrolled. FDG PET/CT was performed from day 6 to day 14 of the onset of symptoms. Depending on FDG PET/CT findings, patients' profiles were classified as "inflammatory" or "low inflammatory." FDG PET/CT data were compared with chest CT evolution and short-term clinical outcome. All inflammatory sites were reported to screen potential extra-pulmonary tropism. Results Thirteen patients were included. Maximum standardized uptake values ranged from 4.7 to 16.3 in lungs. All patients demonstrated increased mediastinal lymph nodes glucose uptake. Three patients (23%) presented mild nasopharyngeal, two patients (15%) bone marrow, and five patients (38%) splenic mild increase in glucose uptake. No patient had significant digestive focal or segmental glucose uptake. There was no significant physiological myocardial glucose uptake in all patients except one. There was no correlation between PET lung inflammatory status and chest CT evolution or short-term clinical outcome. Conclusion Inflammatory process at the presumed peak of the inflammatory phase in COVID-19 patients is obvious in FDG PET/CT scans. Glucose uptake is heterogeneous and typically focused on lungs. Trial registration NCT04441489. Registered 22 June 2020 (retrospectively registered).

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ALTHOUGH THE RISK OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) infection through occupational exposures to blood has received considerable attention, 1 relatively few studies have addressed blood exposure accidents (BEAs) among medical students. [2][3][4][5][6][7] Guidelines for preventing needlestick injuries and administrating postneedlestick HIV prophylaxis are available, 8 but these guidelines may be unfamiliar to medical students. This study investigates BEA exposure, BEA reporting, and use of universal precautions in a population of French medical students. MethodsAn anonymous questionnaire was administered to medical students in the fourth, fifth, and sixth years of training at Nice University, France. Students answered questions regarding the use of gloves, handling of sharps, and personal exposure to needlestick injuries (BEAs). Information on risk reduction behaviors, number of BEAs, BEA reporting, and BEA management was collected. Data were analysed with Epi-Info 6.04a and BMDP software. Results

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