We calculate the quantum Cram\'er--Rao bound for the sensitivity with which one or several parameters, encoded in a general single-mode Gaussian state, can be estimated. This includes in particular the interesting case of mixed Gaussian states. We apply the formula to the problems of estimating phase, purity, loss, amplitude, and squeezing. In the case of the simultaneous measurement of several parameters, we provide the full quantum Fisher information matrix. Our results unify previously known partial results, and constitute a complete solution to the problem of knowing the best possible sensitivity of measurements based on a single-mode Gaussian state

Multimode Gaussian quantum light, which includes multimode squeezed and multipartite quadrature entangled light, is a very general and powerful quantum resource with promising applications in quantum information processing and metrology. In this paper, we determine the ultimate sensitivity in the estimation of any parameter when the information about this parameter is encoded in such light, irrespective of the information extraction protocol used in the estimation and of the measured observable. In addition we show that an appropriate homodyne detection scheme allows us to reach this ultimate sensitivity. We show that, for a given set of available quantum resources, the most economical way to maximize the sensitivity is to put the most squeezed state available in a well-defined light mode. This implies that it is not possible to take advantage of the existence of squeezed fluctuations in other modes, nor of quantum correlations and entanglement between different modes.