Marker enzymes such as acid phosphatase(ACP), alkaline phosphatase(ALP) and aspartate transaminase(AST) levels were estimated in the serum of 60 fibroid patients and 60 non-fibroid patients from UTH, Ado-Ekiti. The age, weight and height of the patients were also considered. Results obtained showed a significant increase in the level of ACP (12.15±6.02 a µ/L), significant decrease in AST (10.24±3.10 a µ/L) level, and no significant difference was recorded in ALP (14.99±2.20 a µ/L) level when compared to the control (10.10±6.15 a µ/L), (12.40±3.11 a µ/L) and (15.52±1.30 a µ/L) respectively. Significant increase in both the age and weight of fibroid patients were also observed which could be related to the etiology of fibroid while height (not significant) may not be related to fibroid. However, this study showed that the activity of ALP does not change in fibroid cases while there are changes in the activities of both ACP and AST.

Objective: Cancer is a major health problem not only in developed countries but also in developing countries like Nigeria. This study was designed to study the status of plasma electrolytes, urea, creatinine, and C-reative proteins (CRPs) in freshly diagnosed cancer patients. , urea, creatinine, and CRP were estimated in four different types of cancer (liver, colon, cervical, and uterine) patients attending Ekiti State University Teaching Hospital Ado Ekiti Nigeria. A total of 250 patients (between age of 45 and 70 years) consisting of 50 patients in each cancer type and 50 normal subjects as control were considered in this study. Methods Results:The result obtained revealed a significant (p<0.05) increase in the plasma levels of Na + , Cl -, creatinine, and CRP in all the cancer types when compared with the control subjects. Plasma urea level decreased significantly in patients with colon (3.16±0.70 mmol/L) and liver (3.03±1.75 mmol/L) cancer when compared with the control subjects (4.80±1.12 mmol/L). K + and HCO 3 _ level was not significantly (p>0.05) different in all cancer types when compared with the control subjects. Conclusion:This study revealed a possible link between plasma electrolytes, creatinine, CRP, urea, and cancer which could be useful in the assessment and management of cancer.

Objective: Cancer is a major health problem not only in developed countries but also in developing countries like Nigeria. This study was designed to study the status of plasma electrolytes, urea, creatinine, and C-reative proteins (CRPs) in freshly diagnosed cancer patients. , urea, creatinine, and CRP were estimated in four different types of cancer (liver, colon, cervical, and uterine) patients attending Ekiti State University Teaching Hospital Ado Ekiti Nigeria. A total of 250 patients (between age of 45 and 70 years) consisting of 50 patients in each cancer type and 50 normal subjects as control were considered in this study. Methods Results:The result obtained revealed a significant (p<0.05) increase in the plasma levels of Na + , Cl -, creatinine, and CRP in all the cancer types when compared with the control subjects. Plasma urea level decreased significantly in patients with colon (3.16±0.70 mmol/L) and liver (3.03±1.75 mmol/L) cancer when compared with the control subjects (4.80±1.12 mmol/L). K + and HCO 3 _ level was not significantly (p>0.05) different in all cancer types when compared with the control subjects. Conclusion:This study revealed a possible link between plasma electrolytes, creatinine, CRP, urea, and cancer which could be useful in the assessment and management of cancer.