Sickle Cell Anaemia (SCA) is a serious inherited blood disorder where the red blood cells, which carry oxygen around the body develop abnormally. The mathematical dynamics of the disease remain poorly understood, as such this paper investigates the mathematical inheritance pattern of the disease by the application of Monte Carlos simulation technique which is a complementary approach to physical simulation Smith's statistical package was used as random number generator in which the simulated birth from different mating indicates that SS has an average of 2.4% neonates, AS has 29.9% and AA has 67.7%. We thus, conclude that eradication of SCA is not visible. However, curative measure of SCA remains paramount.
Sickle Cell Disease (SCD) is a potentially devastating condition that is caused by an autosomal recessive inherited hemoglobinopathy which results in the vaso-occlusive phenomena and hemolysis. Sickle Cell Anaemia (SCA) is the most common form of SCD. As such, this paper provides an insight on the mathematical transmission dynamics of SCA and develops a physical realistic model. A female dominant renewal equation of birth dynamics was developed. Hardy-Weinberg equation is applied to obtain the frequency of different genotype groups for the physical simulation. We realized an average of 70% neonates normal (AA), 27% carrier (AS), and 3% sicklers (SS), which is typically the real world result. This implies that physical simulation is an effective tool in predicting the genetic make-up of any population.
The datasets contained in this article are simulated data with respect to Sickle Cell Anaemia (SCA) in order to examine the mathematical inheritance formation of the SCA disease. The simulation is done using Monte Carlos Simulation (MCS) Technique to complement the Physical Simulation Smith's Statistical (PSSS) package used as random number generator for birth simulation. One hundred and fifty-six (156) births for seven (7) generations were considered in the simulation alongside non-gestating reproductive females with fertile male adults while immigration and emigration are not permitted. These datasets can effectively serve as benchmarks for both health, and marital counselling institutions.
This study assesses the motion and the dynamics of heat propagation in magneto-micropolar fluid along a sheet which vertically stretches on a two-dimensional plane in a porous material. The heat distribution is developed and evaluated under the condition of the prescribed wall temperature, constant magnetic field, thermal radiation, variable heat source and viscous dissipation. The main equations are re-formulated from partial to ordinary derivatives using similarity tools and consequently solved numerically by shooting and the Runge-Kutta Fehlberg approach. The parameters of interest are presented graphically to demonstrate their reactions on the velocity profiles, thermal field and heat transfer mechanism of the problem. The outcomes of the current investigation reveal that the heat transfer appreciates in the presence of higher Prandtl number, temperature exponent term and material parameter but decreases as the magnetic field term soars.Besides, the heat boundary structure expands and heat spread occurs as the thermal radiation, magnetic field and Eckert number terms escalates but a reverse trend is encountered as the Prandtl number, material micropolar term, Grashof number and heat exponent terms grows in magnitude. Under some limiting scenarios, the obtained data strongly correspond to the published studies in the open literature.
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