There are significant point-specific and regional correlations between GCC loss, NFL loss, and deficits on SAP. Using these different data sources together may improve our understanding of glaucomatous damage and aid in the management of patients with glaucoma.
Acral lentiginous melanoma (ALM) is a rare histological subtype of melanoma, accounting for 1%-3% of cutaneous malignant melanomas (CMM) (Bradford et al., 2009;Huang et al., 2020). It was first described by Reed in 1976 as a "distinct clinicopathologic entity… pigmented lesions on the extremities, particularly on plantar regions, like the palms of the hands and soles of the feet" (Reed, 1976). The anatomic descriptor "acral" means extremity while "lentiginous" describes the histologic side-by-side arrangement of melanocytes.Histologically, distinguishing features of ALM include acanthosis, lentiginous proliferation of melanocytes in epidermis, spindle cell
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