Heavy metal pollution in coastal regions has become a serious problem due to significant environmental degradations. In the present study, an algal species, U. lactuca, was investigated to assess the impact of heavy metal pollution on the six different locations along the coastal line of the Sea of Marmara in Istanbul. Heavy metal and mineral nutrient elements such as Ca, Cd, Cu, Fe, K, Mg, Mn, Pb, and Zn were determined using ICP-OES. The following lowest and highest concentrations (mg/kg; dw) were measured in Besides, metal deposition in the plant did not alter the mineral nutrient uptake pattern extensively, indicating relatively less contamination risk in the area. Overall, the comparison of heavy metal contents with seawater and sediment samples in the Ulva species showed that U. lactuca is a suitable plant for biomonitoring studies.