<abstract><sec>
<title>Importance</title>
<p>Twitter represents a growing aspect of the social media experience and is a widely used tool for public education in the 21<sup>st</sup> century. In the last few years, there has been concern about the dissemination of false health information on social media. It is therefore important that we assess the influencers of this health information in the field of cardiology.</p>
</sec><sec>
<title>Objective</title>
<p>We sought to identify the top 100 Twitter influencers within cardiology, characterize them, and examine the relationship between their social media activity and academic influence.</p>
</sec><sec>
<title>Design</title>
<p>Twitter topic scores for the topic search “cardiology” were queried on May 01, 2020 using the Right Relevance application programming interface (API). Based on their scores, the top 100 influencers were identified. Among the cardiologists, their academic h-indices were acquired from Scopus and these scores were compared to the Twitter topic scores.</p>
</sec><sec>
<title>Result</title>
<p>We found out that 88/100 (88%) of the top 100 social media influencers on Twitter were cardiologists. Of these, 63/88 (72%) were males and they practiced mostly in the United States with 50/87 (57%) practicing primarily in an academic hospital. There was a moderately positive correlation between the <italic>h-index</italic> and the Twitter topic score, <italic>r</italic> = +0.32 (<italic>p</italic>-value 0.002).</p>
</sec><sec>
<title>Conclusion</title>
<p>Our study highlights that the top ranked cardiology social media influencers on Twitter are board-certified male cardiologists practicing in academic settings in the US. The most influential on Twitter have a moderate influence in academia. Further research should evaluate the relationship between other academic indices and social media influence.</p>
</sec></abstract>
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