Aim: Extrinsic tooth staining potential of iron replacement therapy causes a belief among the parents that these drugs cause tooth decay. In order to clarify this suspicion, the relationship between iron replacement therapy, dental iron concentrations and tooth decay was examined. Results: There was no significant difference between the DMFT score of children who received regular iron replacement during infancy and who did not recieve. There was not a statistically significant difference between the median iron concentration in the primary teeth of the children who were supplemented with iron in their toddler’s age (10,5 mikrog/gr (5,3-17,3)) and were not supplemented (5,6 mikrog/gr (0,64 – 48,9)). Conclusions: The results of the study showed that iron replacement had no adverse effect on the primary teeth.   How to cite this article: Arat Maden E, Eker İ, Erdem O. Evaluation of the Effects of Iron Containing Supplements on Primary Teeth of Children. Int Dent Res 2019;9(2):46-50.    Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.