Objectives: The objective of this study is to identify the clinical characteristics and the factors affecting the morbidity and mortality of the patients with malignancy and to increase the quality of care and raise awareness of rapid targeted-therapy in the emergency department. Materials and Methods: In our study, cancer patients 18 years of age and older who presented to the emergency department of a university hospital were evaluated prospectively. Patients' demographics, vital signs, characteristics associated with malignancy, examinations performed, and their results, treatments, and length of stay were evaluated. Results: A total of 1283 patients and 1522 presentations were recorded. 51.99% of the patients were male, and 48.01% were female. The overall mean age was 63.05±14.08. The most prevalent symptom was dyspnea (17.94%), and the most common type of cancer was lung cancer (16.23%). In male patients, the most prevalent complaint was fever, and the most common type of cancer was lung cancer (34.63%). In female patients, the most prevalent complaint was dyspnea, and the most common type of cancer was breast cancer (35.25%). The influence of MAP, pulse, Hb levels, uremia, and hypoalbuminemia on mortality and ICU admission was significant. Overall, 41.46% of the patients were hospitalized, and 1.05% of the patients died. The average length of stay was 4.64±6.73 days. Conclusion: Patients with malignancy constitute a significant portion of emergency department admissions. Promoting the emergency physicians' insight into and experience on oncological emergencies would contribute to decreasing the mortality and morbidity of these patients. ÖZET Amaç: Çalışmada acil servis başvuran malignite hastalarının klinik karakteristik özelliklerini, morbidite ve mortalitelerine etki eden faktörleri inceleyerek hastaların bakım kalitesini ve hedefe yönelik hızlı tedavi bilincini artırmayı amaçladık.

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Aim: Previous studies using different methods for PTH measurement have found a mild to moderate correlation between iPTH and gland weight. The aim of this study was to describe the relationship between parathyroid hormone and parathyroid adenoma volume, in patients with parathyroid adenomas as predictive value. Material and Methods: The multicenteric study was prepared by retrospectively collecting data from 244 patients with parathyroid adenoma who underwent parathyroidectomy and followed up between 2010 and 2020. Results: Two hundred forty and four (female/male = 203/41) patients with a mean age of 51.41 [min-max: 17 to 88] years. The mean iPTH concentrations preoperatively were 584.27 ng/L [min-max: 18.9 to 5011ng/L]. The mean diameter of adenoma of patients was 2,865 mm3 [min-max: 0.119 to 42.3 mm3]. After parathyroidectomy, PTH values were reevaluated and found as 47.2 ng/L [min-max: 0.2 to 903 ng/L]. In the patients with large parathyroid adenoma volume, preoperative PTH hormone values were statistically significantly higher (p=0.001). Conclusion: Our current study found a positive association between baseline iPTH levels and adenoma weight. These results suggest that serum iPTH level may be useful in predicting parathyroid adenoma volume.

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