Antibiotic resistance possesses a serious challenge in the treatment of Urinary Tract Infections (UTIs). This study was therefore designed to determine the antibiogram of K. pneumoniae isolated from individuals presenting with UTIs in communities within Enugu state. A cross-sectional study was conducted from February, 2021 to June, 2021 and a total of 735 patients with community-acquired UTIs in Enugu state, Nigeria, were involved in the study. The patients were assessed clinically and microbiologically for Klebsiella pnuemoniae and antibiogram of the isolates were investigated. Out of 77 isolates of Klebsiella pneumaniae obtained, 29 (37.7%) showed multiple resistant to the antibiotics used, whereas 48 (62.3%) were either susceptible or intermediate. Of all the antibiotics tested, meropenem showed the highest recorded sensitivity to the test organism 63(19.93%), whereas the least sensitivity was observed in co-amoxiclav 11 (3.48%). Antibiogram of urinary K. pneumoniae isolated from rural dwellers showed a significantly high resistance to commonly used antibiotics; thus, the need for regular awareness campaign and antimicrobial resistance surveillance to increase knowledge, improve infection control measures, and check abuse of antibiotics.
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