Background Rare disease communities are spread around the globe and segmented by their condition. Little research has been performed on the majority of rare diseases. Most patients who are affected by a rare disease have no research on their condition because of a lack of knowledge due to absence of common groups in the research community. Objective We aimed to develop a safe and secure community of rare disease patients, without geographic or language barriers, to promote research. Methods Cocreation design methodology was applied to build Share4Rare, with consultation and input through workshops from a variety of stakeholders (patients, caregivers, clinicians, and researchers). Results The workshops allowed us to develop a layered version of the platform based on educating patients and caregivers with publicly accessible information, a secure community for the patients and caregivers, and a research section with the purpose of collecting patient information for analysis, which was the core and final value of the platform. Conclusions Rare disease research requires global collaboration in which patients and caregivers have key roles. Collective intelligence methods implemented in digital platforms reduce geographic and language boundaries and involve patients in a unique and universal project. Their contributions are essential to increase the amount of scientific knowledge that experts have on rare diseases. Share4Rare has been designed as a global platform to facilitate the donation of clinical information to foster research that matters to patients with rare conditions. The codesign methods with patients have been essential to create a patient-centric design.

BACKGROUND Rare disease communities are spread around the globe and segmented by their condition. The most of the patients being affected by a rare disease have no research on their condition because of lack of knowledge due to absence of common groups from where to raise knowledge and promote research. OBJECTIVE To build a safe and secure community of rare diseases patients without geographical or language barriers to promote research. METHODS Co-creation design methodology was applied to build the first Share4Rare final version, with consultation and input from a variety of stakeholders (patients, caregivers, clinicians & researchers). RESULTS The workshops allowed us to develop a layered version of the platform, based on educating patients and caregivers with publicly accessible information, a secure community for the patients and caregivers, and a research section with the purpose of collecting patient information for analysis, which was the core and final value of the platform. CONCLUSIONS Rare diseases research requires a global collaboration in which patients and caregivers have a key role. Collective intelligence methods implemented in digital platforms allows to reduce geographical and language boundaries, and involve in a unique and universal project patients. Their contribution is essential to reduce the scientific knowledge that experts have on rare diseases. Share4Rare has been designed as a global platform to facilitate the donation of clinical information to foster research that matters to the patients with rare conditions. The co-design methods with patients have been essential to perform a patient centric design of Share4Rare.